Risk Factors for Abnormal Lung Function
We next examined the association between clinical risk factors and abnormal lung function (Table 3). No significant association was seen between WFA or WFL z-scores at 3 months of age, 6 months of age or 6 months prior to iPFT and lung function z-scores. No significant association was seen between WFA or WFL z-score at 6 months of age and raw lung function values (data not shown). We did not observe any significant association between clinical risk factors and hyperinflation. Consistent with previously reported literature3,28, a history of wheezing (p=0.02) and smoke exposure (p=0.05) were associated with diminished FEV0.5.