What’s Already Known?
Transrectal ultrasound-guided biopsy (TRUS-bx) is one of most common modality to diagnose prostate cancer. Infectious complications after prostate biopsy are rising due to antibiotic usage and fluoroquinolone resistance. Reducing risk of complications is the question to must be answered. Previous studies showed that rectal swaps could decrease infectious due to targeted prophylaxis, however, culture sampling several days prior biopsy is cost effective in routine practice. Additionally, rectal enemas, povidone-iodine and antimicrobial lubricant could decrease infectious complications. Literature suggest that preventive effect of rectal enemas is still debatable.