Funding
This work was supported by the National Key Research and Development Program of China (2018YFC1002900), and the National Natural Science Foundation of China (81520108013, 81771613, 81671488, 81871189). The funders had no involvement in the study design, data collection and analysis, interpretation of data, and preparation of the manuscript. The corresponding authors had full access to all of the data in the study and had the final responsibility to submit for publication.