<div>Dr. Kittipak Jenghua</div><div>Department of Pharmaceutical Care</div><div>School of Pharmaceutical Sciences, University of Phayao</div><div>Tambon Maeka, Muang District, Phayao, 56000</div><div>October 1, 2020</div><div>Dear Dr. Charles Young,</div><div>We wish to submit an original research article entitled “<b>The
prevalence of potentially inappropriate medications for patients with
heart failure (PIMHF) use and its association with non-cardiovascular
co-morbidities in Thai patients with heart failure</b> ” for consideration
by the International Journal of Clinical Practice (IJCP).</div><div>We confirm that this work is original and has not been published
elsewhere, nor is it currently under consideration for publication
elsewhere.</div><div>In this paper, we report on evaluating the prevalence of potentially
inappropriate medications for patients with heart failure (PIMHF) use
and attempt to indicate co-morbidities associated with PIMHF use. This
is significant because heart failure is common in clinical practice and
selection of medication for treating co-morbidities accompanying HF has
become complicated as several medications, which is considered as PIMHF,
may worsen HF, leading to hospitalization. Recently, we have developed a
list of PIMHF containing 47 medication items to use as a screening tool
for medication use in Thai HF patients. Thus, we conducted this study to
reveal the magnitude of the problem on PIMHF prescription in HF patients
with co-morbidities in real clinical practice. We hope that the findings
of this study can lead to develop awareness of medication use in HF
patients having other co-morbidities among healthcare personnel.</div><div>We would also like to inform that our study has been reviewed and
approved by the Institutional Review Board Committee on human research
at Chiangkham hospital (protocol number: 008/2562) and at Lampang
hospital (protocol number: 84/62). Besides, our manuscript has been
professionally proofread by trusted services as an attached certificate.</div><div>We have no conflicts of interest to disclose.</div><div>Please address all correspondence concerning this manuscript to me at<i>kittipak.je@up.ac.th</i></div><div>Thank you for your consideration of this manuscript.</div><div>Sincerely yours,</div><div>Kittipak Jenghua</div>