Health Outcomes
In multivariable models adjusted for condition-specific treatment exposures, demographic factors, BMI, and physical inactivity, all phenotypes of short sleep duration were associated with grade 2-4 pulmonary, endocrine, and gastrointestinal/hepatic conditions (Table 4). For example, short sleep duration alone was associated with a 22-46% increased prevalence of pulmonary, (RR 1.35, 95% CI 1.08-1.69), endocrine (RR 1.22, 95% CI 1.06-1.39), and gastrointestinal/hepatic conditions (RR 1.46, 95% CI 1.18-1.79) (Table 4). Short sleep with a prolonged SOL was associated with neurologic conditions (RR 1.32, 95% CI 1.04-1.68) and short sleep with prolonged WASO with cardiac (RR 1.21, 95% CI 1.02-1.42) and neurologic conditions (RR 1.25, 95% CI 1.01-1.57) (Table 4). All phenotypes of short sleep duration were associated with anxiety (e.g. short sleep duration RR 3.24, 95% CI 1.64-6.41) and depression (e.g. short sleep duration, RR 2.33, 95% CI 1.27-4.27) (Table 4).