Methods
Study Participants
Study participants were recruited from the St. Jude Lifetime Cohort Study (SJLIFE),20 a retrospective cohort of childhood cancer survivors who participate in prospective medical assessments. The cohort was initiated in 2007 and includes survivors of childhood cancer who are ≥5 years post-diagnosis of a pediatric cancer treated at St. Jude Children’s Research Hospital. For the current study, survivors enrolled in SJLIFE who were ≥18 years of age and ≥10 years post diagnosis were recruited for a randomized controlled trial focused on sleep and cognition. We identified and screened 3,348 potentially eligible SJLIFE participants. Among these survivors, 562 refused participation in the intervention and 1,875 did not meet initial study specific inclusion/exclusion criteria (see Supplementary Table S1 intervention inclusion/exclusion criteria). This resulted in 911 participants who completed baseline evaluations to confirm eligibility for the intervention study and who form the study population for the current analysis. All participants provided written informed consent and the study was approved by the Institutional Review Board at St. Jude Children’s Research Hospital.
Measures