Drug-Drug Interactions, Adverse Reactions & Contraindications
Enbrel is not recommended for patients taking cyclophosphamide,
especially for those suffering from Wegener granulomatosis as it can
cause a higher incidence of solid malignancies. Similarly, Enbrel is not
recommended with Sulfasalazine as it can lead to reduction of neutrophil
count. Enbrel should be given to patients with live vaccines
specifically varicella viruses, but it can be considered for
prophylactic treatment as well. Based on clinical trials, Enbrel can
cause adverse reactions for patients with plaque psoriasis, ankylosing
spondylitis, rheumatoid arthritis, psoriatic arthritis, etc. [13].
In terms of contraindication, Enbrel should not be administered to
patients with sepsis.