Statistical analysis
All statistics were analyzed using SPSS software version 22.0 (IBM
Corp., Armonk, NY, USA). Data were presented as means with standard
deviations (SDs) or medians with interquartile ranges (IQRs) and
25th-75th percentiles. The Mann-Whitney U test was used to compare
nonparametric variables and Student’s t -test was used for
parametric data. The paired sample t -test and repeated measure
ANOVA, followed by the post hoc Tukey test, were used to evaluate
changes of variables. Values of p <0.05 were considered
statistically significant.