Limitations:
Our study has potential limitations. The study is single center and was non-randomized and therefore bias related to the strategy of ablation applied for each patient cannot be excluded. Nevertheless, the findings of the present study are important. A strategy of ablation based solely on the use of ablation catheter with single trans-septal, ablation guided by AI based on WACA and additional carina ablation can achieve high rate of first pass isolation safely and with high long-term success rate. Randomized, larger studies are needed to confirm the feasibility of this approach.