WT TLR2KO |
WT TLR2KO |
WT TLR2KO |
WT TLR2KO |
WT TLR2KO |
WT TLR2KO |
WT TLR2KO |
WT TLR2KO |
|
Ctrl
N=7
|
DOX
N=7
|
DOX
N=7
|
DOX+LCZ
N=7
|
Ctrl
N=7
|
DOX
N=7
|
DOX
N=7
|
EF% |
80.14±1.05 |
80.14±1.05 |
75.74±1.08***
|
78.25±1.17###
|
81.08±1.75 |
81.08±1.75 |
79.18±2.01###
|
FS% |
40.26±2.49 |
40.26±2.49 |
35.11±2.11***
|
38.36±2.47###
|
39.27±1.81 |
39.27±1.81 |
38.75±1.41###
|
LVIDd, mm |
2.11±0.28 |
2.11±0.28 |
2.35±0.56**
|
2.18±0.14##
|
2.10±0.58 |
2.10±0.58 |
2.15±0.78
##
|
IVSD, mm |
0.98±0.11 |
0.98±0.11 |
0.95±0.14*
|
0.99±0.22#
|
0.98±0.07 |
0.98±0.07 |
0.99±0.1#
|
PWd, mm |
0.70±0.03 |
0.70±0.03 |
0.67±0.04**
|
0.71±0.13#
|
0.71±0.21 |
0.71±0.21 |
0.71±0.35#
|
E wave, m/s |
0.68±0.05 |
0.68±0.05 |
0.70±0.07**
|
0.69±0.07#
|
0.67±0.08 |
0.67±0.08 |
0.69±0.11#
|
Tei Index |
0.82±0.04 |
0.82±0.04 |
0.80±0.10**
|
0.82±0.12#
|
0.81±0.11 |
0.81±0.11 |
0.82±0.25#
|
IRT, ms |
15.33±1.14 |
15.33±1.14 |
17.28±1.58*
|
14.56±1.97#
|
14.23±1.46 |
14.23±1.46 |
14.28±1.41#
|