Figure 1: Circulating concentration of (A) ALT (IU/l), (B) miR-122 (fM) and (C) K18 (U/L). Data are the first collected samples from the ALISTER study or SAEFRIF trial. Participants include healthy volunteers (n=28), active TB (n=26), latent TB (n=87), NTM infection (n=25) and HIV-TB coinfection (n=59). Data are presented as dot plots. Line shows median and bars show interquartile range. The significance of differences between groups were determined by one-way Kruskal-Wallis ANOVA, (ALT P=0.2; miR-122 P=0.09; K18 P=0.03).