Figure (2): Photomicrographs of testicular tissue specimens stained by H & E (X400).
(A) Transverse testicular section from control group showing normal histological structure of the mature active seminiferous tubules with complete spermatogenic series in the tubular lumen (S).(B) Transverse testicular section of testis from TQ-treated group showing intact histological structure of the seminiferous tubules with complete spermatogenic series. (C) Transverse testicular section of testis from capsaicin-treated group showing intact histological structure of the seminiferous tubules with complete spermatogenic series. (D) Transverse testicular section from acrylamide-treated group showing severe degeneration and necrosis of primary, secondary and spermatid cells lining seminiferous tubule (large arrow), vacuolation of primary spermatocytes lining seminiferous tubules is also noticed (arrow head ). (E) Transverse testicular section from acrylamide-treated group showing vascular changes including interstitial edema (large arrow) and focal hemorrhage (arrow head). Interstitial Leydig cells show pyknosis (star) while spermatogoneal cells lining seminiferous tubules undergo desquamation (double arrow) were also noticed. (F) Transverse testicular section from acrylamide-treated rats showing degenerated necrotic spermatogoneal cells lining seminiferous tubule (small arrow) as well as interstitial edema (large arrow) and vacuolation of Leydig interstitial cells (arrow head). (G) Transverse testicular section from the group that received TQ plus acrylamide showing intact histological structure with complete spermatogenesis in most of the seminiferous tubules.(H) Transverse testicular section from rats co-administered TQ and acrylamide showing congestion of blood vessels in some few seminiferous tubules (large arrow) and pyknosis in the nuclei of some spermatogonial cells (small arrow). (I) Transverse testicular section from animals concurrently treated with capsaicin and acrylamide showing normal intact histological structure of the seminiferous tubules with complete spermatogenic series in the lumen. (G) Transverse testicular section from rats treated with a combination of capsaicin and acrylamide showing few seminiferous with interstitial edema (arrows) and vacuolation of leydig interstitial cells (heads of arrows).