Figure (2): Photomicrographs of testicular tissue specimens
stained by H & E (X400).
(A) Transverse testicular section from control group showing
normal histological structure of the mature active seminiferous tubules
with complete spermatogenic series in the tubular lumen (S).(B) Transverse testicular section of testis from TQ-treated
group showing intact histological structure of the seminiferous tubules
with complete spermatogenic series. (C) Transverse testicular
section of testis from capsaicin-treated group showing intact
histological structure of the seminiferous tubules with complete
spermatogenic series. (D) Transverse testicular section from
acrylamide-treated group showing severe degeneration and necrosis of
primary, secondary and spermatid cells lining seminiferous tubule (large
arrow), vacuolation of primary spermatocytes lining seminiferous tubules
is also noticed (arrow head ). (E) Transverse testicular
section from acrylamide-treated group showing vascular changes including
interstitial edema (large arrow) and focal hemorrhage (arrow head).
Interstitial Leydig cells show pyknosis (star) while spermatogoneal
cells lining seminiferous tubules undergo desquamation (double arrow)
were also noticed. (F) Transverse testicular section from
acrylamide-treated rats showing degenerated necrotic spermatogoneal
cells lining seminiferous tubule (small arrow) as well as interstitial
edema (large arrow) and vacuolation of Leydig interstitial cells (arrow
head). (G) Transverse testicular section from the group that
received TQ plus acrylamide showing intact histological structure with
complete spermatogenesis in most of the seminiferous tubules.(H) Transverse testicular section from rats co-administered TQ
and acrylamide showing congestion of blood vessels in some few
seminiferous tubules (large arrow) and pyknosis in the nuclei of some
spermatogonial cells (small arrow). (I) Transverse testicular
section from animals concurrently treated with capsaicin and acrylamide
showing normal intact histological structure of the seminiferous tubules
with complete spermatogenic series in the lumen. (G) Transverse
testicular section from rats treated with a combination of capsaicin and
acrylamide showing few seminiferous with interstitial edema (arrows) and
vacuolation of leydig interstitial cells (heads of arrows).