Association of urinary LTE4 levels with age and gender in acute
dengue
Of the 120 patients who were recruited during early illness (≤ 4 days of
illness), 48 (40%) were females and 72 (60%) were males. There was no
significant difference in the LTE4 levels between males and females (p =
0.343) (Fig 5a) . However there was a significant positive
correlation between urinary LTE4 levels and age (Spearman r = 0.20 and p
= 0.03) (Fig 5b) . A significant difference (p=0.003) was
observed in the urine LTE4 levels in those who were ≤ 25 years (n=55),
those who were 26 to 40 years (n=31) and those who were ≥ 41 years
(n=33) (Fig 5c ). However, the proportion of those who had DHF
(n=20, 60.6%) was higher in those who were ≥ 41 years, compared to
those who were ≤ 25 years (n=16, 29.1%), which could have accounted for
these changes. (Fig 5c ).