Usefulness of LTE4 in predicting development of DHF in early
illness
As urinary LTE4 levels were higher in patients who proceeded to develop
DHF during early illness (≤ 4 days of illness), we sought to assess if
urinary LTE4 could be used as a predictive marker of subsequent
development of DHF in early illness. Receiver-operator characteristic
(ROC) curves showing the area under the curve (AUC) were generated to
determine the discriminatory performance of LTE4 for DHF in early
illness, which showed an AUC value of 0.67, with a 95% confidence
interval of 0.57 and 0.76, which was significant (p=0.002)(Figure 3) .