Conclusions
We found that urinary LTE4 levels were significantly higher in early
illness in patients, who proceed to develop DHF. The LTE4 levels
continued to rise during the course of illness in patients with DHF,
whereas the levels remained unchanged in those with DF. As there are
cysteinyl leukotriene receptor antagonists available, it would be
imporant to evaluate if these drugs could reduce dengue disease
severity.