Introduction
Idiopathic hyper eosinophilic syndrome (HES) is a rare disease
characterized by sustained increase in eosinophilia. Lesions can affect
various organs and systems. The global prevalence rate is unknown, and
the prognosis is poor. At present, most of the literature reports are
based on cases. Heart involvement may be present in 50% to 60% of
patients, this is called Loffler endocarditis.[1]. Loffler
endocarditis is a serious complication of hyper eosinophilia syndrome,
which is characterized by a special type of fibrotic endocarditis.
Loffler endocarditis is an inflammatory cardiac condition characterized
by eosinophilic infiltration in the heart. The cardiac damage occurs in
three stage processes: the necrotic,
thrombotic, and fibrotic stages. This
unusual but sometimes life-threatening disease is often detected in the
late phase, resulting in no curative strategy available to reverse the
disease process. The overall prognosis of patients with Loffler
endocarditis is very poor. Current treatments include anticoagulation
and anti-eosinophils therapy,surgery only used in selected cases.
Surgical treatment of HES in adolescents is very rare. In this article
we report an 8-year-old girl who was diagnosed as having Loffler
endocarditis in thrombotic phase and treated by surgery successfully.