Acknowledgement and funding

The study was supported by the Deutsche Forschungsgemeinschaft (SFB815, A12 to IT and CRC1039 A03 to IT and CRC1039 Z01 to GG) and the Fraunhofer Cluster of Excellence for immune mediated diseases (CIMD). The funding institution had no role in the conceptualization, design, data collection, analysis, decision to publish, or preparation of the manuscript.