1 INTRODUCTION
COVID-19 (Coronavirus disease), caused by severe acute respiratory coronavirus 2 syndrome (SARS-CoV-2), was first identified in Wuhan , China, in December 2019(1). The World Health Organization declared a public health emergency of international concern regarding this global outbreak of pneumonia on 30 January 2020. Globally, as of 9:37am CEST, 30 May 2020, there have been 5,796,257 confirmed cases of COVID-19, including 362,483deaths, reported to WHO(2). In Bangladesh, as of 4 June 2020, there have been about 52000 confirmed cases of COVID-19 with about 700 deaths. The virus COVID-19 is primarily transmitted between humans through respiratory droplets and contact routes. Analysis of 75,465 COVID-19 cases in China has not reported airborne transmission(3-5). Early moderate signs occurred during the course of the disease offer a chance to early detect COVID-19. Fast identification and accurate treatment have been critical to avoiding the spread of infection(6, 7). At present, transcription polymerase chain reaction (RT-PCR) and real‐time RT-PCR (rRT‐PCR) are used to detect gene expressions of SARS CoV-2. There are three genes expression of SARS CoV-2 such as the RNA-dependent RNA polymerase (RdRp)/helicase (Hel), spike (S), and nucleocapsid (N) genes(8, 9). In Bangladesh, rRT-PCR is used to detect early COVID-19. After a week, point-of-care test kits for Ag and Ab is used to measure the protective level of plasma antibodies ( IgM and IgG). In this study, we reported COVID-19 case of man who had no travel history to COVID-19 prone areas whereas he had the characteristics signs and symptoms of COVID-19. Chest X-ray and rRT-PCR revealed his confirmed COVID-19.