More than 2-fold increase in anaphylaxis incidence between 2009
and 2019
Between 2009 and 2019, there were a total of 2,854 patients admitted
2,961 times with a physician-reported diagnosis of anaphylaxis over the
span of 11 years. Detailed breakdown of the demographics, admissions and
rates of AAI prescriptions of patients per year is shown in Table 1. The
number of admissions (per geographical locations) and proportion of
patients discharged with AAI per year are displayed in Figure 1. The
overall 10-year estimated incidence rate was 3.57 per 100,000
person-years; the male to female ratio was 0.52 and the median age was
46 years (range 0-98 years). The estimated incidence rates per year are
shown in Table 2. The increase in the anaphylaxis incidence rates was
more than 2-fold from 2009 to 2019, with a particularly marked increase
between 2013 and 2014 (2.80 to 4.44 per 100,000 population,
respectively). The increased incidence was also much greater among the
paediatric population (pediatric vs adult: 2.11 vs 2.30 per 100,000
population in 2009 to 7.40 vs 4.18 per 100,000 population in 2019).