Acknowledgments
The authors would like to thank all of the clinicians and families who
made this study possible by providing samples. The authors would also
like to thank Mr. Akitaka Sugishita, Ms. Yoshie Miura, Ms. Hiroko Ono,
and Ms. Chie Amahori for their valuable assistance. The authors
acknowledge the help of the Division for Medical Research Engineering,
Nagoya University Graduate School of Medicine, regarding technical
support with next-generation sequencing. The authors also acknowledge
the help of the Human Genome Center, University of Tokyo, for providing
super-computing resources (http://sc.hgc.jp/shirokane.html).