Anti-D concentration at delivery
At delivery, the variation of anti-D concentration was large, between 14.4 and 184 IU/L, with mean and SD of 60±34 IU/L, Fig 3. Median gestational age of delivery was 40 weeks (38-42 weeks). Five women were recommended additional prophylaxis due to a weak result in the type and screen test at delivery. They had anti-D concentrations between 14.4 and 30 IU/L (3-6 µg/L). Two of the five women had levels below 15 IU/L (14,4 and 14,5). One of the women had high BMI, 34, and both had low concentrations at all measurements. The other three women had concentrations of 27-30 IU/L. In 25/39 FMH was analysed after delivery and the results were negative in all, i.e. below the LOD, 1 mL fetal blood in maternal circulation.
The women were monitored up to 30 days postpartum, showing stable protective levels of anti-D after delivery, Fig. 3. The concentration of anti-D analysed at delivery and in postdelivery samples (n=59) were 61+ 28 IU/L (mean+ SD) after administration of anti-D 1500 IU in gestational week 38+ 1, excluding the five women who got a new dose anti-D at delivery.