Methods
To construct a global AD skin transcriptomic profile comparing
tape-strips to whole skin biopsies, we performed RNA-seq on tape-strips
and biopsies taken from the lesional skin of 20 moderate-to-severe AD
patients and the skin of 20 controls. Differentially expressed genes
(DEGs) were defined by fold-change (FCH)≥2.0 and false discovery
rate<0.05.