Figure 3. The H and E section of right axillary lymph node core needle biopsy (A, x20) show the numerous large atypical cells with horse-shoe shaped nuclei and prominent nucleoli. Immunohistochemistry studies show the neoplastic lymphocytes positive for CD 30 (B, x20), ALK-1 (C, x20), and CD 5 (D, x20); negative for PAX5, CD20, CD3.