References
Aguilar MA, Rodriguez-Arias M, Minarro J (2009) Neurobiological mechanisms of the reinstatement of drug-conditioned place preference. Brain research reviews 59:253-277.
Arevalo S, Prado G, Amaro H (2008) Spirituality, sense of coherence, and coping responses in women receiving treatment for alcohol and drug addiction. Evaluation and program planning 31:113-123.
Assar N, Mahmoudi D, Farhoudian A, Farhadi MH, Fatahi Z, Haghparast A (2016) D1- and D2-like dopamine receptors in the CA1 region of the hippocampus are involved in the acquisition and reinstatement of morphine-induced conditioned place preference. Behavioural brain research 312:394-404.
Ayrout M, Le Billan F, Grange-Messent V, Mhaouty-Kodja S, Lombes M, Chauvin S (2019) Glucocorticoids stimulate hypothalamic dynorphin expression accounting for stress-induced impairment of GnRH secretion during preovulatory period. Psychoneuroendocrinology 99:47-56.
Bahi A, Kusnecov A, Dreyer JL (2008) The role of tissue-type plasminogen activator system in amphetamine-induced conditional place preference extinction and reinstatement. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 33:2726-2734.
Beardsley PM, Howard JL, Shelton KL, Carroll FI (2005) Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in rats. Psychopharmacology 183:118-126.
Bello-Ramirez AM, Nava-Ocampo AA (2004) A QSAR analysis of toxicity of Aconitum alkaloids. Fundamental & clinical pharmacology 18:699-704.
Bobzean SAM, Kokane SS, Butler BD, Perrotti LI (2019) Sex differences in the expression of morphine withdrawal symptoms and associated activity in the tail of the ventral tegmental area. Neuroscience letters 705:124-130.
Bodnar RJ (2010) Endogenous opiates and behavior: 2009. Peptides 31:2325-2359.
Bruchas MR, Land BB, Chavkin C (2010) The dynorphin/kappa opioid system as a modulator of stress-induced and pro-addictive behaviors. Brain research 1314:44-55.
Carey AN, Borozny K, Aldrich JV, Mclaughlin JP (2007) Reinstatement of cocaine place-conditioning prevented by the peptide kappa-opioid receptor antagonist arodyn. European journal of pharmacology 569:84-89.
Chartoff EH, Potter D, Damez-Werno D, Cohen BM, Carlezon WA, Jr. (2008) Exposure to the selective kappa-opioid receptor agonist salvinorin A modulates the behavioral and molecular effects of cocaine in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 33:2676-2687.
Chefer VI, Czyzyk T, Bolan EA, Moron J, Pintar JE, Shippenberg TS (2005) Endogenous kappa-opioid receptor systems regulate mesoaccumbal dopamine dynamics and vulnerability to cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience 25:5029-5037.
Coller JK, Hutchinson MR (2012) Implications of central immune signaling caused by drugs of abuse: Mechanisms, mediators and new therapeutic approaches for prediction and treatment of drug dependence. Pharmacology & therapeutics 134:219-245.
Ezard N, Cecilio ME, Clifford B, Baldry E, Burns L, Day CA, Shanahan M, Dolan K (2018) A managed alcohol program in Sydney, Australia: Acceptability, cost-savings and non-beverage alcohol use. Drug and alcohol review 37 Suppl 1:S184-s194.
Fallon JH, Leslie FM (1986) Distribution of dynorphin and enkephalin peptides in the rat brain. The Journal of comparative neurology 249:293-336.
Fan H, Li TF, Gong N, Wang YX (2015) Shanzhiside methylester, the principle effective iridoid glycoside from the analgesic herb Lamiophlomis rotata, reduces neuropathic pain by stimulating spinal microglial β-endorphin expression. Neuropharmacology:S0028390815301027.
Fanselow MS, Dong HW (2010) Are the dorsal and ventral hippocampus functionally distinct structures? Neuron 65:7-19.
Freeman KB, Naylor JE, Prisinzano TE, Woolverton WL (2014) Assessment of the kappa opioid agonist, salvinorin A, as a punisher of drug self-administration in monkeys. Psychopharmacology 231:2751-2758.
Garaschuk O, Verkhratsky A (2019) Physiology of Microglia. Methods in molecular biology (Clifton, NJ) 2034:27-40.
Goeldner C, Lutz PE, Darcq E, Halter T, Clesse D, Ouagazzal AM, Kieffer BL (2011) Impaired emotional-like behavior and serotonergic function during protracted abstinence from chronic morphine. Biological psychiatry 69:236-244.
Gouveia K, Hurst JL Optimising reliability of mouse performance in behavioural testing: the major role of non-aversive handling. Scientific Reports 7:44999.
Hooke LP, He L, Lee NM (1995) Dynorphin A modulates acute and chronic opioid effects. Journal of Pharmacology & Experimental Therapeutics 273:292-297.
Hu X, Li P, Guo Y, Wang H, Leak RK, Chen S, Gao Y, Chen J (2012) Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia. Stroke 43:3063-3070.
Huang Q, Sun ML, Chen Y, Li XY, Wang YX (2017a) Concurrent bullatine A enhances morphine antinociception and inhibits morphine antinociceptive tolerance by indirect activation of spinal kappa-opioid receptors. Journal of ethnopharmacology 196:151-159.
Huang Q, Mao XF, Wu HY, Li TF, Sun ML, Liu H, Wang YX (2016) Bullatine A stimulates spinal microglial dynorphin A expression to produce anti-hypersensitivity in a variety of rat pain models. Journal of Neuroinflammation 13.
Huang Q, Mao XF, Wu HY, Liu H, Sun ML, Wang X, Wang YX (2017b) Cynandione A attenuates neuropathic pain through p38beta MAPK-mediated spinal microglial expression of beta-endorphin. Brain, behavior, and immunity 62:64-77.
Huang S-N, Wei J, Huang L-T, Ju P-J, Chen J, Wang Y-X (2020a) Bulleyaconitine A Inhibits Visceral Nociception and Spinal Synaptic Plasticity through Stimulation of Microglial Release of Dynorphin A. Neural Plasticity 2020:1484087.
Huang SN, Yang B, Ma L, Huang LT, Ju PJ, Wei J, Ali U, Wang YX, Chen J (2020b) Bulleyaconitine A Exerts Antianxiety and Antivisceral Hypersensitivity Effects. Frontiers in pharmacology 11:328.
Hutchinson MR, Lewis SS, Coats BD, Skyba DA, Crysdale NY, Berkelhammer DL, Brzeski A, Northcutt A, Vietz CM, Judd CM, Maier SF, Watkins LR, Johnson KW (2009) Reduction of opioid withdrawal and potentiation of acute opioid analgesia by systemic AV411 (ibudilast). Brain, behavior, and immunity 23:240-250.
Hylden JL, Wilcox GL (1980) Intrathecal morphine in mice: a new technique. European journal of pharmacology 67:313-316.
Kampman K, Jarvis M (2015) American Society of Addiction Medicine (ASAM) National Practice Guideline for the Use of Medications in the Treatment of Addiction Involving Opioid Use. Journal of addiction medicine 9:358-367.
Khaleghzadeh-Ahangar H, Haghparast A (2015) Intra-accumbal CB1 receptor blockade reduced extinction and reinstatement of morphine. Physiology & behavior 149:212-219.
Khaleghzadeh-Ahangar H, Haghparast A (2017) Intra-accumbal Cannabinoid Agonist Attenuated Reinstatement but not Extinction Period of Morphine-Induced Conditioned Place Preference; Evidence for Different Characteristics of Extinction Period and Reinstatement. Neurochemical research 42:3321-3330.
Kobayashi K, Imagama S, Ohgomori T, Hirano K, Uchimura K, Sakamoto K, Hirakawa A, Takeuchi H, Suzumura A, Ishiguro N, Kadomatsu K (2013) Minocycline selectively inhibits M1 polarization of microglia. Cell Death Dis 4:e525.
Kovacs KJ (2012) Microglia and drug-induced plasticity in reward-related neuronal circuits. Frontiers in molecular neuroscience 5:74.
LeGates TA, Kvarta MD, Tooley JR, Francis TC, Lobo MK, Creed MC, Thompson SM (2018) Reward behaviour is regulated by the strength of hippocampus-nucleus accumbens synapses. Nature 564:258-262.
Leitermann RJ, Terashvili M, Mizoguchi H, Wu HE, Chen F, Clithero A, Tseng LF (2004) Increased release of immunoreactive dynorphin A1-17 from the spinal cord after intrathecal treatment with endomorphin-2 in anesthetized rats. European journal of pharmacology 504:177-183.
Lenard NR, Roerig SC (2005) Development of antinociceptive tolerance and physical dependence following morphine i.c.v. infusion in mice. European journal of pharmacology 527:71-76.
Li T-F, Gong N, Wang Y-X (2016a) Ester Hydrolysis Differentially Reduces Aconitine-Induced Anti-hypersensitivity and Acute Neurotoxicity: Involvement of Spinal Microglial Dynorphin Expression and Implications for Aconitum Processing. Frontiers in pharmacology 7:367-367.
Li TF, Fan H, Wang YX (2016b) Aconitum-Derived Bulleyaconitine A Exhibits Antihypersensitivity Through Direct Stimulating Dynorphin A Expression in Spinal Microglia. The journal of pain : official journal of the American Pain Society 17:530-548.
Li TF, Wu HY, Wang YR, Li XY, Wang YX (2017) Molecular signaling underlying bulleyaconitine A (BAA)-induced microglial expression of prodynorphin. Sci Rep 7:45056.
Liu R, Huang X-P, Yeliseev A, Xi J, Roth B (2013) Novel Molecular Targets of Dezocine and Their Clinical Implications. Anesthesiology 120.
Maisonneuve IM, Archer S, Glick SD (1994) U50,488, a kappa opioid receptor agonist, attenuates cocaine-induced increases in extracellular dopamine in the nucleus accumbens of rats. Neuroscience letters 181:57-60.
Marszalek-Grabska M, Gibula-Bruzda E, Bodzon-Kulakowska A, Suder P, Gawel K, Filarowska J, Listos J, Danysz W, Kotlinska JH (2018) Effects of the Positive Allosteric Modulator of Metabotropic Glutamate Receptor 5, VU-29, on Impairment of Novel Object Recognition Induced by Acute Ethanol and Ethanol Withdrawal in Rats. Neurotoxicity research 33:607-620.
Meng J, Zhang X, Wu H, Bu J, Shi C, Deng C, Mao Y (2012) Morphine-induced conditioned place preference in mice: Metabolomic profiling of brain tissue to find “molecular switch” of drug abuse by gas chromatography/mass spectrometry. Analytica Chimica Acta 710:125-130.
Meshul CK, McGinty JF (2000) Kappa opioid receptor immunoreactivity in the nucleus accumbens and caudate-putamen is primarily associated with synaptic vesicles in axons. Neuroscience 96:91-99.
Miguel-Hidalgo JJ, Wei J, Andrew M, Overholser JC, Jurjus G, Stockmeier CA, Rajkowska G (2002) Glia pathology in the prefrontal cortex in alcohol dependence with and without depressive symptoms. Biological psychiatry 52:1121-1133.
Murphy NP, Ly HT, Maidment NT (1996) Intracerebroventricular orphanin FQ/nociceptin suppresses dopamine release in the nucleus accumbens of anaesthetized rats. Neuroscience 75:1-4.
Mysels D, Sullivan MA (2009) The kappa-opiate receptor impacts the pathophysiology and behavior of substance use. The American journal on addictions 18:272-276.
Negus SS, Schrode K, Stevenson GW (2008) Micro/kappa opioid interactions in rhesus monkeys: implications for analgesia and abuse liability. Experimental and clinical psychopharmacology 16:386-399.
Nestler EJ, Hope BT, Widnell KL (1993) Drug addiction: a model for the molecular basis of neural plasticity. Neuron 11:995-1006.
Nocjar C, Zhang J, Feng P, Panksepp J (2012) The social defeat animal model of depression shows diminished levels of orexin in mesocortical regions of the dopamine system, and of dynorphin and orexin in the hypothalamus. Neuroscience 218:138-153.
Patyal R, Woo EY, Borgland SL (2012) Local hypocretin-1 modulates terminal dopamine concentration in the nucleus accumbens shell. Frontiers in behavioral neuroscience 6:82.
Pfeiffer A, Brantl V, Herz A, Emrich HM (1986) Psychotomimesis mediated by kappa opiate receptors. Science (New York, NY) 233:774-776.
Qi C, Guo B, Ren K, Yao H, Wang M, Sun T, Cai G, Liu H, Li R, Luo C, Wang W, Wu S (2018) Chronic inflammatory pain decreases the glutamate vesicles in presynaptic terminals of the nucleus accumbens. Molecular pain 14:1744806918781259.
Qu Y, Qu P (1994) Aconitane derivatives used as a medication to treat addiction. In: US Patent NO: 5,290,784.
Reiss D, Ceredig RA, Secher T, Boue J, Barreau F, Dietrich G, Gaveriaux-Ruff C (2017) Mu and delta opioid receptor knockout mice show increased colonic sensitivity. European journal of pain (London, England) 21:623-634.
Riahi E, Khodagholi F, Haghparast A (2013) Role of dorsal hippocampal orexin-1 receptors in associating morphine reward with contextual stimuli. Behavioural pharmacology 24:237-248.
Robbins TW, Ersche KD, Everitt BJ (2008) Drug addiction and the memory systems of the brain. Annals of the New York Academy of Sciences 1141:1-21.
Ruzza C, Holanda VA, Gavioli EC, Trapella C, Calo G (2019) NOP agonist action of cebranopadol counteracts its liability to promote physical dependence. Peptides 112:101-105.
Schwarzer C (2009) 30 years of dynorphins–new insights on their functions in neuropsychiatric diseases. Pharmacology & therapeutics 123:353-370.
Sebastian, T., Peters, Michael, T., Bowen, Kathrin, Bohrer, Iain, S. (2016) Oxytocin inhibits ethanol consumption and ethanol-induced dopamine release in the nucleus accumbens. Addiction Biology.
Shi X, Barr JL, von Weltin E, Wolsh C, Unterwald EM (2019) Differential Roles of Accumbal GSK3beta in Cocaine versus Morphine-Induced Place Preference, U50,488H-Induced Place Aversion, and Object Memory. The Journal of pharmacology and experimental therapeutics 371:339-347.
Shippenberg TS, Zapata A, Chefer VI (2007a) Dynorphin and the pathophysiology of drug addiction. Pharmacology & Therapeutics 116:306-321.
Shippenberg TS, Zapata A, Chefer VI (2007b) Dynorphin and the pathophysiology of drug addiction. Pharmacology & therapeutics 116:306-321.
Shirazy M, RayatSanati K, Jamali S, Motamedi F, Haghparast A (2020) Role of orexinergic receptors in the dentate gyrus of the hippocampus in the acquisition and expression of morphine-induced conditioned place preference in rats. Behavioural brain research 379:112349.
Sun M-L, Ao J-P, Wang Y-R, Huang Q, Li T-F, Li X-Y, Wang Y-X (2018a) Lappaconitine, a C18-diterpenoid alkaloid, exhibits antihypersensitivity in chronic pain through stimulation of spinal dynorphin A expression. Psychopharmacology 235:2559-2571.
Takemori AE, Loh HH, Lee NM (1993) Suppression by dynorphin A and [des-Tyr1]dynorphin A peptides of the expression of opiate withdrawal and tolerance in morphine-dependent mice. The Journal of pharmacology and experimental therapeutics 266:121-124.
Tang XC, Liu XJ, Wei-Hua LU, Wang MD, Ai-Ling LI (1986) STUDIES ON THE ANALGESIC ACTION AND PHYSICAL DEPENDENCE OF BULLEYACONITINE A. Acta Pharmaceutica Sinica.
Tran TH, Griffin BL, Stone RH, Vest KM, Todd TJ (2017) Methadone, Buprenorphine, and Naltrexone for the Treatment of Opioid Use Disorder in Pregnant Women. Pharmacotherapy 37:824-839.
Volkow ND, Fowler JS, Wang GJ, Baler R, Telang F (2009) Imaging dopamine’s role in drug abuse and addiction. Neuropharmacology 56 Suppl 1:3-8.
Wahlert A, Funkelstein L, Fitzsimmons B, Yaksh T, Hook V (2013) Spinal astrocytes produce and secrete dynorphin neuropeptides. Neuropeptides 47:109-115.
Wakabayashi Y, Nakada T, Murata K, Ohkura S, Mogi K, Navarro VM, Clifton DK, Mori Y, Tsukamura H, Maeda K, Steiner RA, Okamura H (2010) Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat. The Journal of neuroscience : the official journal of the Society for Neuroscience 30:3124-3132.
Wang CF, Gerner P, Wang SY, Wang GK (2007) Bulleyaconitine A isolated from aconitum plant displays long-acting local anesthetic properties in vitro and in vivo. Anesthesiology 107:82-90.
Wilson RS, DiGeorge WS (1993) Methadone combined with clonidine versus clonidine alone in opiate detoxification. Journal of substance abuse treatment 10:529-535.
Wingo T, Nesil T, Choi JS, Li MD (2016) Novelty Seeking and Drug Addiction in Humans and Animals: From Behavior to Molecules. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 11:456-470.
Woody GE, Luborsky L, McLellan AT, O’Brien CP, Beck AT, Blaine J, Herman I, Hole A (1983) Psychotherapy for opiate addicts. Does it help? Archives of general psychiatry 40:639-645.
Wu D, Teismann P, Ischiropoulos H, Vilaperelló M, Przedborski S, Tieu K, Vadseth C, Jacksonlewis V, Choi DH (2002) Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. 22:1763.
Wu HY, Tang XQ, Mao XF, Wang YX (2017) Autocrine Interleukin-10 Mediates Glucagon-Like Peptide-1 Receptor-Induced Spinal Microglial β-Endorphin Expression. The Journal of neuroscience : the official journal of the Society for Neuroscience 37:11701-11714.
Wu HY, Mao XF, Tang XQ, Usman A, Evhy A, Hao L, Li XY, Wang YX (2018) Spinal interleukin-10 produces antinociception in neuropathy through microglial β-endorphin expression, separated from antineuroinflammation. Brain Behavior & Immunity:S0889159118302319-.
Wu X, Zhao N, Bai F, Li C, Liu C, Wei J, Zong W, Yang L, Ryabinin AE, Ma Y, Wang J (2016) Morphine-induced conditioned place preference in rhesus monkeys: Resistance to inactivation of insula and extinction. Neurobiology of Learning and Memory 131:192-200.
Xie MX, Zhu HQ, Pang RP, Wen BT, Liu XG (2018) Mechanisms for therapeutic effect of bulleyaconitine A on chronic pain. Molecular pain 14:1744806918797243.
Yamada K, Ono Y, Kubo KY, Yamamoto T, Onozuka M (2013) Occlusal Disharmony Transiently Impairs Learning and Memory in the Mouse by Increasing Dynorphin A Levels in the Amygdala. The Tohoku journal of experimental medicine 230:49-57.
Yuferov V, Fussell D, LaForge KS, Nielsen DA, Gordon D, Ho A, Leal SM, Ott J, Kreek MJ (2004) Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction. Pharmacogenetics 14:793-804.
Zhang H, Shi Y-G, Woods J, Watson S, Ko M-C (2007) Central kappa-opioid receptor-mediated antidepressant-like effects of nor-Binaltorphimine: behavioral and BDNF mRNA expression studies. European journal of pharmacology 570:89-96.
Zhang JY, Gong N, Huang JL, Guo LC, Wang YX (2013) Gelsemine, a principal alkaloid from Gelsemium sempervirens Ait., exhibits potent and specific antinociception in chronic pain by acting at spinal alpha 3 glycine receptors. Pain 154:2452-2462.
Zhu X, Sun W, Li X, Tan S, Zhang X (2015) Effects of spatial memory on morphine CPP and locomotor sensitization in mice. Physiology & behavior 149:187-191.