References
Aguilar MA, Rodriguez-Arias M, Minarro J (2009) Neurobiological
mechanisms of the reinstatement of drug-conditioned place preference.
Brain research reviews 59:253-277.
Arevalo S, Prado G, Amaro H (2008) Spirituality, sense of coherence, and
coping responses in women receiving treatment for alcohol and drug
addiction. Evaluation and program planning 31:113-123.
Assar N, Mahmoudi D, Farhoudian A, Farhadi MH, Fatahi Z, Haghparast A
(2016) D1- and D2-like dopamine receptors in the CA1 region of the
hippocampus are involved in the acquisition and reinstatement of
morphine-induced conditioned place preference. Behavioural brain
research 312:394-404.
Ayrout M, Le Billan F, Grange-Messent V, Mhaouty-Kodja S, Lombes M,
Chauvin S (2019) Glucocorticoids stimulate hypothalamic dynorphin
expression accounting for stress-induced impairment of GnRH secretion
during preovulatory period. Psychoneuroendocrinology 99:47-56.
Bahi A, Kusnecov A, Dreyer JL (2008) The role of tissue-type plasminogen
activator system in amphetamine-induced conditional place preference
extinction and reinstatement. Neuropsychopharmacology : official
publication of the American College of Neuropsychopharmacology
33:2726-2734.
Beardsley PM, Howard JL, Shelton KL, Carroll FI (2005) Differential
effects of the novel kappa opioid receptor antagonist, JDTic, on
reinstatement of cocaine-seeking induced by footshock stressors vs
cocaine primes and its antidepressant-like effects in rats.
Psychopharmacology 183:118-126.
Bello-Ramirez AM, Nava-Ocampo AA (2004) A QSAR analysis of toxicity of
Aconitum alkaloids. Fundamental & clinical pharmacology 18:699-704.
Bobzean SAM, Kokane SS, Butler BD, Perrotti LI (2019) Sex differences in
the expression of morphine withdrawal symptoms and associated activity
in the tail of the ventral tegmental area. Neuroscience letters
705:124-130.
Bodnar RJ (2010) Endogenous opiates and behavior: 2009. Peptides
31:2325-2359.
Bruchas MR, Land BB, Chavkin C (2010) The dynorphin/kappa opioid system
as a modulator of stress-induced and pro-addictive behaviors. Brain
research 1314:44-55.
Carey AN, Borozny K, Aldrich JV, Mclaughlin JP (2007) Reinstatement of
cocaine place-conditioning prevented by the peptide kappa-opioid
receptor antagonist arodyn. European journal of pharmacology 569:84-89.
Chartoff EH, Potter D, Damez-Werno D, Cohen BM, Carlezon WA, Jr. (2008)
Exposure to the selective kappa-opioid receptor agonist salvinorin A
modulates the behavioral and molecular effects of cocaine in rats.
Neuropsychopharmacology : official publication of the American College
of Neuropsychopharmacology 33:2676-2687.
Chefer VI, Czyzyk T, Bolan EA, Moron J, Pintar JE, Shippenberg TS (2005)
Endogenous kappa-opioid receptor systems regulate mesoaccumbal dopamine
dynamics and vulnerability to cocaine. The Journal of neuroscience : the
official journal of the Society for Neuroscience 25:5029-5037.
Coller JK, Hutchinson MR (2012) Implications of central immune signaling
caused by drugs of abuse: Mechanisms, mediators and new therapeutic
approaches for prediction and treatment of drug dependence. Pharmacology
& therapeutics 134:219-245.
Ezard N, Cecilio ME, Clifford B, Baldry E, Burns L, Day CA, Shanahan M,
Dolan K (2018) A managed alcohol program in Sydney, Australia:
Acceptability, cost-savings and non-beverage alcohol use. Drug and
alcohol review 37 Suppl 1:S184-s194.
Fallon JH, Leslie FM (1986) Distribution of dynorphin and enkephalin
peptides in the rat brain. The Journal of comparative neurology
249:293-336.
Fan H, Li TF, Gong N, Wang YX (2015) Shanzhiside methylester, the
principle effective iridoid glycoside from the analgesic herb
Lamiophlomis rotata, reduces neuropathic pain by stimulating spinal
microglial β-endorphin expression. Neuropharmacology:S0028390815301027.
Fanselow MS, Dong HW (2010) Are the dorsal and ventral hippocampus
functionally distinct structures? Neuron 65:7-19.
Freeman KB, Naylor JE, Prisinzano TE, Woolverton WL (2014) Assessment of
the kappa opioid agonist, salvinorin A, as a punisher of drug
self-administration in monkeys. Psychopharmacology 231:2751-2758.
Garaschuk O, Verkhratsky A (2019) Physiology of Microglia. Methods in
molecular biology (Clifton, NJ) 2034:27-40.
Goeldner C, Lutz PE, Darcq E, Halter T, Clesse D, Ouagazzal AM, Kieffer
BL (2011) Impaired emotional-like behavior and serotonergic function
during protracted abstinence from chronic morphine. Biological
psychiatry 69:236-244.
Gouveia K, Hurst JL Optimising reliability of mouse performance in
behavioural testing: the major role of non-aversive handling. Scientific
Reports 7:44999.
Hooke LP, He L, Lee NM (1995) Dynorphin A modulates acute and chronic
opioid effects. Journal of Pharmacology & Experimental Therapeutics
273:292-297.
Hu X, Li P, Guo Y, Wang H, Leak RK, Chen S, Gao Y, Chen J (2012)
Microglia/macrophage polarization dynamics reveal novel mechanism of
injury expansion after focal cerebral ischemia. Stroke 43:3063-3070.
Huang Q, Sun ML, Chen Y, Li XY, Wang YX (2017a) Concurrent bullatine A
enhances morphine antinociception and inhibits morphine antinociceptive
tolerance by indirect activation of spinal kappa-opioid receptors.
Journal of ethnopharmacology 196:151-159.
Huang Q, Mao XF, Wu HY, Li TF, Sun ML, Liu H, Wang YX (2016) Bullatine A
stimulates spinal microglial dynorphin A expression to produce
anti-hypersensitivity in a variety of rat pain models. Journal of
Neuroinflammation 13.
Huang Q, Mao XF, Wu HY, Liu H, Sun ML, Wang X, Wang YX (2017b)
Cynandione A attenuates neuropathic pain through p38beta MAPK-mediated
spinal microglial expression of beta-endorphin. Brain, behavior, and
immunity 62:64-77.
Huang S-N, Wei J, Huang L-T, Ju P-J, Chen J, Wang Y-X (2020a)
Bulleyaconitine A Inhibits Visceral Nociception and Spinal Synaptic
Plasticity through Stimulation of Microglial Release of Dynorphin A.
Neural Plasticity 2020:1484087.
Huang SN, Yang B, Ma L, Huang LT, Ju PJ, Wei J, Ali U, Wang YX, Chen J
(2020b) Bulleyaconitine A Exerts Antianxiety and Antivisceral
Hypersensitivity Effects. Frontiers in pharmacology 11:328.
Hutchinson MR, Lewis SS, Coats BD, Skyba DA, Crysdale NY, Berkelhammer
DL, Brzeski A, Northcutt A, Vietz CM, Judd CM, Maier SF, Watkins LR,
Johnson KW (2009) Reduction of opioid withdrawal and potentiation of
acute opioid analgesia by systemic AV411 (ibudilast). Brain, behavior,
and immunity 23:240-250.
Hylden JL, Wilcox GL (1980) Intrathecal morphine in mice: a new
technique. European journal of pharmacology 67:313-316.
Kampman K, Jarvis M (2015) American Society of Addiction Medicine (ASAM)
National Practice Guideline for the Use of Medications in the Treatment
of Addiction Involving Opioid Use. Journal of addiction medicine
9:358-367.
Khaleghzadeh-Ahangar H, Haghparast A (2015) Intra-accumbal CB1 receptor
blockade reduced extinction and reinstatement of morphine. Physiology &
behavior 149:212-219.
Khaleghzadeh-Ahangar H, Haghparast A (2017) Intra-accumbal Cannabinoid
Agonist Attenuated Reinstatement but not Extinction Period of
Morphine-Induced Conditioned Place Preference; Evidence for Different
Characteristics of Extinction Period and Reinstatement. Neurochemical
research 42:3321-3330.
Kobayashi K, Imagama S, Ohgomori T, Hirano K, Uchimura K, Sakamoto K,
Hirakawa A, Takeuchi H, Suzumura A, Ishiguro N, Kadomatsu K (2013)
Minocycline selectively inhibits M1 polarization of microglia. Cell
Death Dis 4:e525.
Kovacs KJ (2012) Microglia and drug-induced plasticity in reward-related
neuronal circuits. Frontiers in molecular neuroscience 5:74.
LeGates TA, Kvarta MD, Tooley JR, Francis TC, Lobo MK, Creed MC,
Thompson SM (2018) Reward behaviour is regulated by the strength of
hippocampus-nucleus accumbens synapses. Nature 564:258-262.
Leitermann RJ, Terashvili M, Mizoguchi H, Wu HE, Chen F, Clithero A,
Tseng LF (2004) Increased release of immunoreactive dynorphin A1-17 from
the spinal cord after intrathecal treatment with endomorphin-2 in
anesthetized rats. European journal of pharmacology 504:177-183.
Lenard NR, Roerig SC (2005) Development of antinociceptive tolerance and
physical dependence following morphine i.c.v. infusion in mice. European
journal of pharmacology 527:71-76.
Li T-F, Gong N, Wang Y-X (2016a) Ester Hydrolysis Differentially Reduces
Aconitine-Induced Anti-hypersensitivity and Acute Neurotoxicity:
Involvement of Spinal Microglial Dynorphin Expression and Implications
for Aconitum Processing. Frontiers in pharmacology 7:367-367.
Li TF, Fan H, Wang YX (2016b) Aconitum-Derived Bulleyaconitine A
Exhibits Antihypersensitivity Through Direct Stimulating Dynorphin A
Expression in Spinal Microglia. The journal of pain : official journal
of the American Pain Society 17:530-548.
Li TF, Wu HY, Wang YR, Li XY, Wang YX (2017) Molecular signaling
underlying bulleyaconitine A (BAA)-induced microglial expression of
prodynorphin. Sci Rep 7:45056.
Liu R, Huang X-P, Yeliseev A, Xi J, Roth B (2013) Novel Molecular
Targets of Dezocine and Their Clinical Implications. Anesthesiology 120.
Maisonneuve IM, Archer S, Glick SD (1994) U50,488, a kappa opioid
receptor agonist, attenuates cocaine-induced increases in extracellular
dopamine in the nucleus accumbens of rats. Neuroscience letters
181:57-60.
Marszalek-Grabska M, Gibula-Bruzda E, Bodzon-Kulakowska A, Suder P,
Gawel K, Filarowska J, Listos J, Danysz W, Kotlinska JH (2018) Effects
of the Positive Allosteric Modulator of Metabotropic Glutamate Receptor
5, VU-29, on Impairment of Novel Object Recognition Induced by Acute
Ethanol and Ethanol Withdrawal in Rats. Neurotoxicity research
33:607-620.
Meng J, Zhang X, Wu H, Bu J, Shi C, Deng C, Mao Y (2012)
Morphine-induced conditioned place preference in mice: Metabolomic
profiling of brain tissue to find “molecular switch” of drug abuse by
gas chromatography/mass spectrometry. Analytica Chimica Acta
710:125-130.
Meshul CK, McGinty JF (2000) Kappa opioid receptor immunoreactivity in
the nucleus accumbens and caudate-putamen is primarily associated with
synaptic vesicles in axons. Neuroscience 96:91-99.
Miguel-Hidalgo JJ, Wei J, Andrew M, Overholser JC, Jurjus G, Stockmeier
CA, Rajkowska G (2002) Glia pathology in the prefrontal cortex in
alcohol dependence with and without depressive symptoms. Biological
psychiatry 52:1121-1133.
Murphy NP, Ly HT, Maidment NT (1996) Intracerebroventricular orphanin
FQ/nociceptin suppresses dopamine release in the nucleus accumbens of
anaesthetized rats. Neuroscience 75:1-4.
Mysels D, Sullivan MA (2009) The kappa-opiate receptor impacts the
pathophysiology and behavior of substance use. The American journal on
addictions 18:272-276.
Negus SS, Schrode K, Stevenson GW (2008) Micro/kappa opioid interactions
in rhesus monkeys: implications for analgesia and abuse liability.
Experimental and clinical psychopharmacology 16:386-399.
Nestler EJ, Hope BT, Widnell KL (1993) Drug addiction: a model for the
molecular basis of neural plasticity. Neuron 11:995-1006.
Nocjar C, Zhang J, Feng P, Panksepp J (2012) The social defeat animal
model of depression shows diminished levels of orexin in mesocortical
regions of the dopamine system, and of dynorphin and orexin in the
hypothalamus. Neuroscience 218:138-153.
Patyal R, Woo EY, Borgland SL (2012) Local hypocretin-1 modulates
terminal dopamine concentration in the nucleus accumbens shell.
Frontiers in behavioral neuroscience 6:82.
Pfeiffer A, Brantl V, Herz A, Emrich HM (1986) Psychotomimesis mediated
by kappa opiate receptors. Science (New York, NY) 233:774-776.
Qi C, Guo B, Ren K, Yao H, Wang M, Sun T, Cai G, Liu H, Li R, Luo C,
Wang W, Wu S (2018) Chronic inflammatory pain decreases the glutamate
vesicles in presynaptic terminals of the nucleus accumbens. Molecular
pain 14:1744806918781259.
Qu Y, Qu P (1994) Aconitane derivatives used as a medication to treat
addiction. In: US Patent NO: 5,290,784.
Reiss D, Ceredig RA, Secher T, Boue J, Barreau F, Dietrich G,
Gaveriaux-Ruff C (2017) Mu and delta opioid receptor knockout mice show
increased colonic sensitivity. European journal of pain (London,
England) 21:623-634.
Riahi E, Khodagholi F, Haghparast A (2013) Role of dorsal hippocampal
orexin-1 receptors in associating morphine reward with contextual
stimuli. Behavioural pharmacology 24:237-248.
Robbins TW, Ersche KD, Everitt BJ (2008) Drug addiction and the memory
systems of the brain. Annals of the New York Academy of Sciences
1141:1-21.
Ruzza C, Holanda VA, Gavioli EC, Trapella C, Calo G (2019) NOP agonist
action of cebranopadol counteracts its liability to promote physical
dependence. Peptides 112:101-105.
Schwarzer C (2009) 30 years of dynorphins–new insights on their
functions in neuropsychiatric diseases. Pharmacology & therapeutics
123:353-370.
Sebastian, T., Peters, Michael, T., Bowen, Kathrin, Bohrer, Iain, S.
(2016) Oxytocin inhibits ethanol consumption and ethanol-induced
dopamine release in the nucleus accumbens. Addiction Biology.
Shi X, Barr JL, von Weltin E, Wolsh C, Unterwald EM (2019) Differential
Roles of Accumbal GSK3beta in Cocaine versus Morphine-Induced Place
Preference, U50,488H-Induced Place Aversion, and Object Memory. The
Journal of pharmacology and experimental therapeutics 371:339-347.
Shippenberg TS, Zapata A, Chefer VI (2007a) Dynorphin and the
pathophysiology of drug addiction. Pharmacology & Therapeutics
116:306-321.
Shippenberg TS, Zapata A, Chefer VI (2007b) Dynorphin and the
pathophysiology of drug addiction. Pharmacology & therapeutics
116:306-321.
Shirazy M, RayatSanati K, Jamali S, Motamedi F, Haghparast A (2020) Role
of orexinergic receptors in the dentate gyrus of the hippocampus in the
acquisition and expression of morphine-induced conditioned place
preference in rats. Behavioural brain research 379:112349.
Sun M-L, Ao J-P, Wang Y-R, Huang Q, Li T-F, Li X-Y, Wang Y-X (2018a)
Lappaconitine, a C18-diterpenoid alkaloid, exhibits antihypersensitivity
in chronic pain through stimulation of spinal dynorphin A expression.
Psychopharmacology 235:2559-2571.
Takemori AE, Loh HH, Lee NM (1993) Suppression by dynorphin A and
[des-Tyr1]dynorphin A peptides of the expression of opiate
withdrawal and tolerance in morphine-dependent mice. The Journal of
pharmacology and experimental therapeutics 266:121-124.
Tang XC, Liu XJ, Wei-Hua LU, Wang MD, Ai-Ling LI (1986) STUDIES ON THE
ANALGESIC ACTION AND PHYSICAL DEPENDENCE OF BULLEYACONITINE A. Acta
Pharmaceutica Sinica.
Tran TH, Griffin BL, Stone RH, Vest KM, Todd TJ (2017) Methadone,
Buprenorphine, and Naltrexone for the Treatment of Opioid Use Disorder
in Pregnant Women. Pharmacotherapy 37:824-839.
Volkow ND, Fowler JS, Wang GJ, Baler R, Telang F (2009) Imaging
dopamine’s role in drug abuse and addiction. Neuropharmacology 56 Suppl
1:3-8.
Wahlert A, Funkelstein L, Fitzsimmons B, Yaksh T, Hook V (2013) Spinal
astrocytes produce and secrete dynorphin neuropeptides. Neuropeptides
47:109-115.
Wakabayashi Y, Nakada T, Murata K, Ohkura S, Mogi K, Navarro VM, Clifton
DK, Mori Y, Tsukamura H, Maeda K, Steiner RA, Okamura H (2010)
Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate
nucleus participate in generation of periodic oscillation of neural
activity driving pulsatile gonadotropin-releasing hormone secretion in
the goat. The Journal of neuroscience : the official journal of the
Society for Neuroscience 30:3124-3132.
Wang CF, Gerner P, Wang SY, Wang GK (2007) Bulleyaconitine A isolated
from aconitum plant displays long-acting local anesthetic properties in
vitro and in vivo. Anesthesiology 107:82-90.
Wilson RS, DiGeorge WS (1993) Methadone combined with clonidine versus
clonidine alone in opiate detoxification. Journal of substance abuse
treatment 10:529-535.
Wingo T, Nesil T, Choi JS, Li MD (2016) Novelty Seeking and Drug
Addiction in Humans and Animals: From Behavior to Molecules. Journal of
neuroimmune pharmacology : the official journal of the Society on
NeuroImmune Pharmacology 11:456-470.
Woody GE, Luborsky L, McLellan AT, O’Brien CP, Beck AT, Blaine J, Herman
I, Hole A (1983) Psychotherapy for opiate addicts. Does it help?
Archives of general psychiatry 40:639-645.
Wu D, Teismann P, Ischiropoulos H, Vilaperelló M, Przedborski S, Tieu K,
Vadseth C, Jacksonlewis V, Choi DH (2002) Blockade of microglial
activation is neuroprotective in the
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson
disease. 22:1763.
Wu HY, Tang XQ, Mao XF, Wang YX (2017) Autocrine Interleukin-10 Mediates
Glucagon-Like Peptide-1 Receptor-Induced Spinal Microglial β-Endorphin
Expression. The Journal of neuroscience : the official journal of the
Society for Neuroscience 37:11701-11714.
Wu HY, Mao XF, Tang XQ, Usman A, Evhy A, Hao L, Li XY, Wang YX (2018)
Spinal interleukin-10 produces antinociception in neuropathy through
microglial β-endorphin expression, separated from antineuroinflammation.
Brain Behavior & Immunity:S0889159118302319-.
Wu X, Zhao N, Bai F, Li C, Liu C, Wei J, Zong W, Yang L, Ryabinin AE, Ma
Y, Wang J (2016) Morphine-induced conditioned place preference in rhesus
monkeys: Resistance to inactivation of insula and extinction.
Neurobiology of Learning and Memory 131:192-200.
Xie MX, Zhu HQ, Pang RP, Wen BT, Liu XG (2018) Mechanisms for
therapeutic effect of bulleyaconitine A on chronic pain. Molecular pain
14:1744806918797243.
Yamada K, Ono Y, Kubo KY, Yamamoto T, Onozuka M (2013) Occlusal
Disharmony Transiently Impairs Learning and Memory in the Mouse by
Increasing Dynorphin A Levels in the Amygdala. The Tohoku journal of
experimental medicine 230:49-57.
Yuferov V, Fussell D, LaForge KS, Nielsen DA, Gordon D, Ho A, Leal SM,
Ott J, Kreek MJ (2004) Redefinition of the human kappa opioid receptor
gene (OPRK1) structure and association of haplotypes with opiate
addiction. Pharmacogenetics 14:793-804.
Zhang H, Shi Y-G, Woods J, Watson S, Ko M-C (2007) Central kappa-opioid
receptor-mediated antidepressant-like effects of nor-Binaltorphimine:
behavioral and BDNF mRNA expression studies. European journal of
pharmacology 570:89-96.
Zhang JY, Gong N, Huang JL, Guo LC, Wang YX (2013) Gelsemine, a
principal alkaloid from Gelsemium sempervirens Ait., exhibits potent and
specific antinociception in chronic pain by acting at spinal alpha 3
glycine receptors. Pain 154:2452-2462.
Zhu X, Sun W, Li X, Tan S, Zhang X (2015) Effects of spatial memory on
morphine CPP and locomotor sensitization in mice. Physiology & behavior
149:187-191.