Strengths and limitations
Although our study provides evidence of the role of GLS in the
echocardiographic evaluation of different types of ventricular geometry,
some strengths and limitations must be recognized. The strength of this
study is based on echocardiographic measurements made in these subjects,
in which we combined GLS and conventional echocardiographic parameters
according to standardized protocols and current guidelines. Furthermore,
we were able to identify that a specific type of ventricular geometry
was closely associated with LV and LA dysfunction, indicating an
opportunity for early detection of the associated complications that
these subjects could develop.
However, our study has some limitations. First, the number of subjects
included is small, and a larger sample size is required to replicate and
validate the results. Second, we were unable to obtain biochemical
values or use another imaging method to correlate these associations
with our findings and conduct a follow-up of these subjects to assess
prognosis and cardiac complications.