Strengths and limitations
Although our study provides evidence of the role of GLS in the echocardiographic evaluation of different types of ventricular geometry, some strengths and limitations must be recognized. The strength of this study is based on echocardiographic measurements made in these subjects, in which we combined GLS and conventional echocardiographic parameters according to standardized protocols and current guidelines. Furthermore, we were able to identify that a specific type of ventricular geometry was closely associated with LV and LA dysfunction, indicating an opportunity for early detection of the associated complications that these subjects could develop.
However, our study has some limitations. First, the number of subjects included is small, and a larger sample size is required to replicate and validate the results. Second, we were unable to obtain biochemical values or use another imaging method to correlate these associations with our findings and conduct a follow-up of these subjects to assess prognosis and cardiac complications.