2.1 Patients
We performed a retrospective observational study to investigate the
impact of donor CSF3R polymorphisms on the clinical outcomes of acute
leukemia patients who underwent HLA-matched sibling HSCT or
unmanipulated haploidentical allo-HSCT at the Peking University
Institute of Hematology from April 2014 to April 2015. A total of 273
patients between the ages of three to sixty-two years old were enrolled
in the present study, and all cases were diagnosed based on the World
Health Organization diagnosis criteria. The study was conducted in
accordance with the Declaration of Helsinki and was approved by the
Institutional Review Board of Peking University.
All patients provided informed consent for the treatment under a
protocol reviewed and approved by the Peking University Institute of
Hematology. The patient and transplantation characteristics are
summarized in Table 1 .