2.1 Patients
We performed a retrospective observational study to investigate the impact of donor CSF3R polymorphisms on the clinical outcomes of acute leukemia patients who underwent HLA-matched sibling HSCT or unmanipulated haploidentical allo-HSCT at the Peking University Institute of Hematology from April 2014 to April 2015. A total of 273 patients between the ages of three to sixty-two years old were enrolled in the present study, and all cases were diagnosed based on the World Health Organization diagnosis criteria. The study was conducted in accordance with the Declaration of Helsinki and was approved by the Institutional Review Board of Peking University.
All patients provided informed consent for the treatment under a protocol reviewed and approved by the Peking University Institute of Hematology. The patient and transplantation characteristics are summarized in Table 1 .