Introduction
Primary cutaneous CD4+ small to medium T-cell lymphoproliferative
disorder is rare, accounting for only 2-3% of all primary cutaneous
lymphomas. In 2006, the World Health Organization (WHO) revised the name
of this condition from primary cutaneous CD4+ small to medium
pleomorphic T-cell lymphoma to its current name to indicate its
uncertain malignant potential. The disease is indolent and localized,
rarely showing systemic involvement (1-3). The typical lesion is a
solitary skin-colored papule or nodule involving the head or neck; it
usually grows rapidly but remains asymptomatic, with most patients being
in their 50s-60s (4-7). Histopathological findings show dense
infiltration of CD4+ small or medium T-cell lymphocytes in the dermis or
subcutis area (1, 2). Suggested treatments include an excisional biopsy,
intralesional steroid injection, or radiotherapy; the prognosis is
excellent (4, 7, 8). Herein, we report a rare case of primary cutaneous
CD4+ small/medium T-cell lymphoproliferative disorder.