Comparison of the International Association of the Diabetes and
Pregnancy Study Group (IADPSG) criteria for diagnosis of gestational
diabetes mellitus against a ‘one-stop’ diagnostic test: A Prospective
Descriptive Cross Sectional study
Abstract
Objective: The aim of this study was to investigate the utility of a
single value non fasting glucose tolerance test as described by the
Diabetes in Pregnancy Study Group of India (DIPSI) in detecting GDM
Design: A Prospective Descriptive Cross Sectional study Setting: A
Tertiary care maternity hospital in Sri Lanka. Sample: A sample of 165
pregnant women between 24-28 weeks of gestation was recruited Method:
All women had the DIPSI and standard OGTT tests performed within a one
week and results compared using standard non parametric tests. Main
outcome measures:DIPSI and IADPSG criteria were compared using
sensitivity, specificity and area under the ROC curve. Results:
According to the IADPSG criteria 20% (33/165) had GDM, compared to
22.4% (37/165) detected by DIPSI. Sensitivity of DIPSI criteria was
64% while specificity was 88%. The area under receiver operator curve
was 0.8. The mean satisfaction for DIPSI was of 8.9 ± 0.4, compared to
4.7 ± 1.3 for OGTT (p<0.001). Analysis of false positives
showed that it was mainly due to elevated fasting values in the IADPSG
criteria. Conclusion: Although DIPSI has a low sensitivity compared to
the IADPSG criteria, area under the ROC curve is 0.80 indicating its
utility for diagnosing GDM. It has additional advantages of allowing a
diagnosis of GDM in a single visit and high acceptability among women.
Funding: This study was self-funded Key words : Gestational Diabetes
Mellitus, Diabetes in Pregnancy Study Group India, Oral Glucose
Tolerence Test