Conclusion
Significant proportion of Indian children on ALL maintenance
chemotherapy developed severe infection and hypoglobulinaemia. However,
hypoglobulinaemia did not significantly increase the risk of severe
infection. Younger children and female gender had significantly
increased risk of severe infection during maintenance. Respiratory
infections were the most common infection during maintenance phase and
contributed to 66% of infection related deaths.
Conflict of interest – None
Acknowledgement - None
The data that support the findings of this study are available from the
corresponding author upon reasonable request.