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\begin{document}

\title{Exit strategy of COVID-19 crisis and pathways of Vaccination}



\author[1]{Indrani Roy}%
\affil[1]{University College London * Correspondence}%


\vspace{-1em}



  
  \date{May 08, 2024}


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\begin{abstract}
~ ~ ~ ~ ~ There is a strong coordinated effort by vaccination groups all
over the world to put an end to the current crisis of COVID-19. The Mass
vaccination first started in the UK on 8th December 2020 and soon
afterward covered all of the globe. Now sufficient data are available to
analyse and compare some results to explore many aftereffects of
vaccination. Some influence variables on transmissions of the disease
were discussed e.g., mass vaccination, lockdown and seasonality. To
address seasonality, similarities between COVID-19 and seasonal Flu are
discussed to gain useful insight. Like Flu, seasonality was shown to
play a dominant role in transmissions of COVID-19 in the Eu-rope and US.
In terms of mass vaccination, adverse reactions after vaccination
received attention, as health and safety issues of the general public
are of prime importance. Apart from direct side effects, the secondary
effect of mass vaccination needs attention too. After the initiation of
vaccination programme , almost all countries experienced a sudden surge
of transmission and most countries had to impose strict lockdown
measures. Many countries, those showed a low prevalence of the disease,
suddenly showed a steep jump after the onset of mass vaccination. Some
countries even followed a synchronized pattern between the rate of
transmissions and the variation of vaccine doses; the pattern seemed
distinct with the sudden steep rise/fall in vaccine doses (e.g.,
countries India, Indonesia among others). In that context, fast mutation
of the virus and new variants after mass vaccination and possible
mechanisms/consequences were discussed.

~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~Balanced discussion, critical and open analyses
are desperately needed in the current crucial stage. Debating,
questioning and criticism are always the foundation of good science and
the main pillars to its progress. Following that objective, it is an
effort to explore pragmatically, areas relating to the effectiveness of
the COVID-19 vaccine and the exit strategy via the pathway of
vaccination. Policymakers, academics, patients and common people will be
greatly benefitted from such critical, transparent and balanced
analyses.%
\end{abstract}%



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