Analysis of the 6-OHDA-lesion
TH immunostaining in the striatum and the SNc was used to evaluate the degree of the dopaminergic lesion. There was a marked reduction of the dopaminergic neurons in the SNc and TH-positive fibers in the lesioned striata (Supplementary Fig. 1) compared to the no-lesioned rat striata. There was no difference in the extent of the lesion between the animals in each group.