Analysis of the 6-OHDA-lesion
TH immunostaining in the striatum and the SNc was used to evaluate the
degree of the dopaminergic lesion. There was a marked reduction of the
dopaminergic neurons in the SNc and TH-positive fibers in the lesioned
striata (Supplementary Fig. 1) compared to the no-lesioned rat striata.
There was no difference in the extent of the lesion between the animals
in each group.