Study limitations:
Results of this present study should be considered with regard to the inherent limitations resulting in the design of this retrospective single-center observational analysis of a historical series of selected patients with GUCH. Data collection was not optimal, in terms of clinical and echocardiographic parameters collected during follow-up, without specific protocol of follow-up. Thereby, data were not collected at the same time of follow-up, and were not complete because of patients lost from follow-up. Mean time of follow-up is low and longer follow-up is required to draw consistent conclusions from this case series.