Practising self-injection
It is unclear whether practising injecting adrenaline using an empty syringe at clinic appointments has any effect on outcomes for people at risk of anaphylaxis because the certainty of evidence is very low. One trial found that adolescents who practised felt more comfortable self-injecting than those who did not practise (very low certainty, supplement S6b).11Shemesh E, D’Urso C, Knight C, Rubes M, Picerno KM, Posillico AM, Atal Z, Annunziato RA, Sicherer SH. Food-Allergic Adolescents at Risk for Anaphylaxis: A Randomized Controlled Study of Supervised Injection to Improve Comfort with Epinephrine Self-Injection. J Allergy Clin Immunol Pract 2017;5(2):391-397.e4.