Severe reactions within 1 hour of prophylactic adrenaline for snake bite
anti-venom
|
Children and adults
|
43% reduction (p<0.05)
|
OR 0.57
(0.43 to 0.75)
|
Very Low
|
Unknown impact
|
1 trial
(n = 1007)
(de Silva 2011)
|
Severe reactions within 48 hours of prophylactic adrenaline for snake
bite anti-venom
|
Children and adults
|
Range 8% to 38% reduction (p<0.05)
|
RR in one study 0 (0 to 1.3)
OR in another study 0.62
(0.51 to 0.74)
|
Low
|
May reduce
|
2 trials
(n = 1112)
(Premawardhena 1999, de Silva 2011)
|
Severe reactions within 1 hour of prophylactic hydrocortisone for snake
bite anti-venom
|
Children and adults
|
0.5% increase (p>0.05)
|
OR 0.86
(0.60 to 1.24)
|
Very low
|
Unknown impact
|
1 trial
(n = 1007)
(de Silva 2011)
|
Moderate and severe reactions within 48 hours of prophylactic
hydrocortisone for snake bite anti-venom
|
Children and adults
|
23% reduction (p>0.05)
|
Not reported
|
Very Low
|
Unknown impact
|
1 trial
(n = 52)
(Gawarammana 2004)
|
Moderate and severe reactions within 48 hours of prophylactic
hydrocortisone plus chlorpheniramine for snake bite anti-venom
|
Children and adults
|
23% reduction (p>0.05)
|
Not reported
|
Very low
|
Unknown impact
|
1 trial
(n = 52)
(Gawarammana 2004)
|
Severe reactions within 1 hour of prophylactic promethazine
(antihistamine) for snake bite anti-venom
|
Children and adults
|
2.9% reduction (p>0.05)
|
OR 0.81
(0.51 to 1.30)
|
Very low
|
Unknown impact
|
1 trial
(n = 1007)
(de Silva 2011)
|
Anaphylactic reactions within 24 hours of prophylactic promethazine
(antihistamine) for snake bite anti-venom
|
Children and adults
|
1% reduction (p>0.05)
|
Not reported
|
Very low
|
Unknown impact
|
1 trial
(n = 101)
(Fan 1999)
|