Baseline Characteristics
A total of 2,374 patients underwent cryoballoon ablation for the treatment of AF during the study period. Of this total, 1,194 patients followed a SDD protocol and 1,180 patients were observed during an ONS. Patient demographics of each group are presented in Table 2 . The SDD cohort was significantly younger (64±11 versus 66±10; p< 0.0001), had lower BMI (30±6 versus 31±6; p< 0.0001) and CHA2DS2-VASc scores (1.4±1.0 versus 2.2±1.4; p< 0.0002), and had less chronic heart failure (10% versus 16%; p<0.0001) than the ONS cohort. There was no difference in sex (69% versus 67% male; p=0.3), diabetes (18% versus 21%; p=0.2) or history of transient ischemic attack (5% versus 6%; p=0.4) between SDD and ONS, respectively.