Key messages
  1. current diagnostic methods are inadequate to predict cross-reactivity between crustaceans and mollusks
  2. the detection of mollusks hypersensitivity must still rely on skin tests with fresh material (and oral challenges where possible);
  3. clinically, there is no need to exclude a priori mollusks from shrimp allergic patients’ diet,
  4. albeit rarely, primary sensitization to mollusks seems possible