Is corticosteroid treatment before surgery for chronic
rhinosinusitis with nasal polyps recommended during the pandemic? And if
so, intranasal or oral?
The use of intranasal corticosteroids does not seem to have a negative
impact on symptoms and/or development of COVID-19.116Therefore, intranasal corticosteroid treatment should be continued
perioperatively if possible. The use of corticosteroids either during an
exacerbation or perioperatively should be carefully considered on a
‘per-patient’ basis. Recent guidance from the WHO has advised against
the use of systemic corticosteroids if COVID-19 is suspected due to
concerns that these agents may impair innate antiviral immune
responses.125