Does allergic rhinitis impact the susceptibility of SARS-CoV-2 infection?
There are no conclusive data on the impact of allergic rhinitis on COVID-19 susceptibility116. However, a recent study with 24 allergic rhinitis patients demonstrated a reduction of ACE2 expression in nasal brush samples following an allergen challenge.46 Also, this study reported lower ACE2-expression in the epithelium of asthmatic patients. Altogether, these data suggest that allergic rhinitis patients may have lower risk of SARS-CoV-2 infection as compared to non-allergic individuals, but further studies are needed.