Basophil activation test: mechanisms and considerations for use in clinical trials and clinical practice
Running title: BAT in allergy research and clinical practice
Alexandra F. Santos1,2,3,4, Oral Alpan5, Hans-Jürgen Hoffmann6, 7
1Department of Women and Children’s Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King’s College London, London, United Kingdom
2Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King’s College London, London, United Kingdom
3Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom
4Children’s Allergy Service, Evelina London Children’s Hospital, Guy’s and St Thomas’ Hospital, London, United Kingdom
5Amerimmune, Fairfax, VA, U.S.A.
6Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
7Department of Respiratory Diseases and Allergy, Aarhus University Hospital, Aarhus, Denmark