Systematic reviews of the evidence
Three key questions were addressed: (i) What are the challenges and specific needs of adolescents and young adults with allergic conditions, including asthma, food allergy and anaphylaxis, allergic rhino-conjunctivitis, atopic dermatitis, chronic urticaria, allergic gastrointestinal disease, as well as those with complex multisystem allergic disease? (ii) What specific strategies have proven useful to improve self-management and wellbeing in this population? (iii) What generic approaches are helpful when managing adolescents and young adults? The first two were pursued through two formal systematic reviews (SRs) of the evidence with a cut-off date of February 10, 2019.7,8 The final question was assessed by a SR of the evidence-based adolescent and young adult guidelines from the last 5 years with a cut-off date of June 21, 2019. Individual studies from these guidelines were accessed to determine level of evidence and grade of recommendation. The TF members continued to track evidence published after our systematic review cut-off date and, where relevant, studies were considered by the TF chairs.