LIMITATIONS
The present study was a non-randomized, observational, post hoc, and
retrospective dual-center study with a relatively small sample size. The
slightly older age and higher rates of coronary heart disease and prior
bleeding history were observed in the DAPT group, but DAPT regimen
allowed similar net clinical benefit and fewer bleeding events in this
study. TEE follow-up was not available for all patients, not analyzed in
a central laboratory, and the timing was different between the two
centers. This may have led to an underreporting of DRT and peri-device
leaks for both treatment arms. Nevertheless, there were no differences
in the rate of incomplete TEE follow-up between the ACT and DAPT group.
Hence, potential adverse findings not discovered are supposed to be
distributed similarly between the two groups.