Demographics and clinical features |
Demographics and
clinical features |
Demographics and clinical features |
Demographics and clinical features |
Demographics and
clinical features |
Age at LAAC (years), mean ± SD |
76.6±7.6 |
78.4±7.2 |
75.3±7.7 |
<0.01 |
Body mass index (kg/m²), mean ± SD |
29.3±5.8 |
29.3±6.3 |
28.3±5.4 |
0.95 |
Female sex, n (%) |
114 (21.8) |
75 (34.1) |
99 (32.6) |
0.78 |
Coronary artery disease, n (%) |
273 (52.1) |
126 (57.3) |
147 (48.4) |
0.05 |
Prior PCI/CAGB, n (%) |
220 (42.0) |
95 (43.2) |
125 (41.1) |
0.65 |
Serum creatinine level (mg/dl), mean ± SD |
1.4±0.7 |
1.3±0.8 |
1.4±0.7 |
0.12 |
Paroxysmal AF, n (%) |
182 (36.1) |
79 (35.9) |
103 (33.9) |
0.64 |
LV ejection fraction, % |
54.7±10.4 |
52.4±12.2 |
56.4±8.6 |
<0.01 |
Stroke risk |
Stroke risk |
Stroke risk |
Stroke risk |
Stroke risk |
CHA2DS2-VASc score, mean ± SD |
4.6±1.6 |
4.8±1.5 |
4.5±1.7 |
0.01 |
CHADS2 score, mean ± SD |
3.0±1.1 |
3.0±1.1 |
3.0±1.2 |
0.70 |
Prior stroke/TIA/Systemic embolism, n (%) |
123 (23.5) |
44 (20.0) |
79
(26.0) |
0.12 |
Congestive heart failure, n (%) |
167 (31.9) |
78 (35.5) |
89 (29.3) |
0.15 |
Arterial hypertension, n (%) |
485 (92.6) |
207 (94.1) |
278 (91.5) |
0.31 |
Age ≥75 years, n (%) |
347 (66.2) |
166 (75.5) |
181 (59.5) |
<0.01 |
Vascular disease, n (%) |
324 (61.8) |
137 (62.3) |
187 (61.5) |
0.93 |
Diabetes mellitus, n (%) |
173 (33.0) |
75 (34.1) |
98 (32.2) |
0.71 |
Bleeding risk |
Bleeding risk |
Bleeding risk |
Bleeding risk |
Bleeding risk |
HAS-BLED score, mean ± SD |
3.3±0.9 |
3.3±0.7 |
3.4±1.0 |
0.68 |
Age ≥65 years, n (%) |
492 (93.9) |
216 (98.2) |
276 (90.8) |
<0.01 |
History of hemorrhagic/bleeding tendencies, n (%) |
435 (83.8) |
184
(83.6) |
255 (83.9) |
>0.99 |
Prior bleeding (≥major), n (%) |
309 (59.0) |
142 (64.6) |
167 (54.9) |
0.03 |
Intracranial, n (%) |
41 (7.8) |
13 (5.9) |
28 (9.2) |
0.19 |
Gastrointestinal, n (%) |
149 (28.4) |
62 (28.2) |
87 (28.6) |
0.92 |
Other site, n (%) |
119 (22.7) |
67 (30.5) |
52 (17.1) |
<0.01 |
Arterial hypertension ≥160mmHg, n (%) |
41 (7.8) |
18 (8.2) |
23 (7.6) |
0.87 |
Renal dysfunction, n (%) |
40 (7.6) |
11 (5.0) |
29 (9.5) |
0.07 |
Liver dysfunction, n (%) |
47 (9.0) |
9 (4.1) |
38 (12.5) |
<0.01 |
Labile INR, n (%) |
26 (5.0) |
13 (5.9) |
13 (4.3) |
0.42 |
Drugs with predisposition to bleeding, n (%) |
489 (93.3) |
214 (97.3) |
275 (90.5) |
<0.01 |
Alcohol intake >8 U/week, n (%) |
49 (9.4) |
17 (7.7) |
32
(10.5) |
0.29 |