Summary
Carnivore protoparvovirus 1 is one of the most important
pathogens affecting both wild and domestic carnivores. Here, we reported
the genetic characterization of canine parvovirus strains from a rescued
guiña (Leopardus guigna ) and domestic dogs from Chile. Guiña
sequence was classified as CPV-2c and phylogenetic analysis of the
complete coding genome showed that the guiña CPV-2c strain share a
recent common ancestor with Chilean domestic dogs strains. These viruses
presented >99% identity and showed three changes in the
NS1 protein, CHL-17 V596A, CHL-71 E661K and CHL-guigna L582F. This is
the first detection and genetic characterization of CPV-2c infection in
guiña worldwide and one of the few comparative studies that undoubtedly
determine that the source of infection were domestic dogs. The current
findings highlight that guiña is a susceptible species to
protoparvovirus infection and that domestic dogs represent an important
thread to its conservation. The CPV cross-species transmission between
domestic dogs and guiña should be taken into account for protection
programs of this endangerous species.
Keywords: Canine parvovirus, Leopardus guigna ,
protoparvovirus 1, phylogeny, genetic characterization