Target insensitive mutation collection by literature mining
To obtain the reported insensitive mutations in four targets associated with insecticide resistance, we first collected published literature from the NCBI PubMed database. For collection of literature relevant to target mutations in VGSC, we searched against NCBI PubMed with the term: ((“VGSC” [Abstract]) OR “voltage gated sodium channel” [Abstract]) AND “insecticide resistance” [Abstract]). For collection of literature relevant to target mutations in AChE, we searched against PubMed with the term: ((“AChE” [Abstract]) OR “acetylcholinesterase” [Abstract]) AND “insecticide resistance” [Abstract]). For collection of literature relevant to target mutations in RyR, we searched against PubMed with the term: ((“RyR” [Abstract]) OR “ryanodine receptor” [Abstract]) AND “insecticide resistance” [Abstract]). Finally, for collection of literature relevant to target mutations in nAChR, we searched against PubMed with the term: ((“nAChR” [Abstract]) OR “nicotinic acetylcholine receptor” [Abstract]) AND “insecticide resistance” [Abstract]).