Age, y |
63.0 (52.0, 72.0) |
66.0 (54.0, 75.0) |
61.5 (49.0, 69.0) |
0.02 |
Male sex |
120 (50.2%) |
61 (54.0%) |
59 (46.8%) |
0.27 |
Symptoms |
|
|
|
|
Fever |
189 (79.1%) |
89 (78.8%) |
100 (79.4%) |
0.91 |
Cough |
191 (79.9%) |
87 (77.0%) |
104 (82.5%) |
0.29 |
Sputum |
125 (52.3%) |
52 (46.0%) |
73 (57.9%) |
0.07 |
Dyspnea |
86 (36.0%) |
44 (38.9%) |
42 (33.3%) |
0.37 |
Palpitation |
29 (12.1%) |
18 (15.9%) |
11 (8.7%) |
0.09 |
Fatigue |
81 (33.9%) |
37 (32.7%) |
44 (34.9%) |
0.72 |
Diarrhea |
53 (22.2%) |
30 (26.5%) |
23 (18.3%) |
0.12 |
Nausea and vomiting |
16 (6.7%) |
6 (5.3%) |
10 (7.9%) |
0.42 |
Comorbidity |
|
|
|
|
Hypertension |
90 (37.7%) |
42 (37.2%) |
48 (38.1%) |
0.88 |
Diabetes |
30 (12.6%) |
13 (11.5%) |
17 (13.5%) |
0.64 |
Cardiac disease a
|
30 (12.6%) |
15 (13.3%) |
15
(11.9%) |
0.75 |
COPD |
15 (6.3%) |
7 (6.2%) |
8 (6.3%) |
0.96 |
Chronic renal insufficiency |
3 (1.3%) |
1 (0.9%) |
2 (1.6%) |
0.63 |
Immunosuppression b
|
6 (2.5%) |
4 (3.5%) |
2
(1.6%) |
0.34 |
Severity score and laboratory finding upon admission |
Severity score
and laboratory finding upon admission |
Severity score and laboratory
finding upon admission |
Severity score and laboratory finding upon
admission |
|
APACHE II score |
5.0 (3.0, 8.0) |
6.0 (4.0, 8.0) |
5.0 (2.0, 7.0) |
<0.01 |
SOFA score |
0.0 (0.0, 2.0) |
0.0 (0.0, 2.0) |
0.0 (0.0, 2.0) |
0.95 |
WBC count, ×109 /L |
5.9 (4.7, 7.7) |
5.6 (4.6, 7.8) |
5.9 (4.8, 7.5) |
0.66 |
Lymphocyte count, ×109 /L |
1.3 (0.9, 1.7) |
1.2 (0.8,
1.5) |
1.4 (0.9, 1.8) |
<0.01 |
Platelet count, ×109 /L |
229.0 (168.0, 304.0) |
224.0
(164.0, 314.0) |
229.0 (174.0, 304.0) |
0.70 |
Creatinine level, μmol/L |
69.0 (57.0, 82.0) |
68.0 (57.0, 83.0) |
70.0
(57.0, 80.0) |
0.97 |
hs-CRP, mg/L |
5.4 (1.2, 41.7) |
8.9 (1.7, 49.5) |
3.6 (0.9, 36.0) |
0.03 |
AST level, U/L |
25.0 (19.0, 37.0) |
25.0 (19.0, 39.0) |
26.0 (19.0,
34.0) |
0.67 |
Creatine kinase level, U/L |
56.0 (36.0, 96.0) |
53.0 (35.0, 103.0) |
56.5 (41.0, 90.0) |
0.22 |
CK-MB, ng/mL |
0.7 (0.4, 1.5) |
0.8 (0.4, 1.7) |
0.7 (0.4, 1.3) |
0.69 |
IL-6, pg/mL |
3.8 (1.7, 11.8) |
4.1 (2.0, 21.4) |
3.6 (1.5, 10.8) |
0.08 |
Time to virological result, d |
Time to virological result, d |
|
|
|
From illness onset to diagnosis |
7.0 (3.0, 13.0) |
4.0 (2.0, 8.0) |
10.0 (6.0, 16.0) |
<0.01 |
From illness onset to ART start |
5.0 (1.0, 12.0) |
4.0 (1.0, 9.0) |
7.0
(1.0, 14.0) |
<0.01 |
From illness onset to admission |
15.0 (10.0, 21.0) |
10.0 (7.0, 15.0) |
19.0 (14.0, 31.0) |
<0.01 |
Viral shedding duration c
|
26.0 (20.0, 34.0) |
20.0
(15.0, 22.0) |
34.0 (29.0, 43.0) |
<0.01 |
Treatment or complication |
|
|
|
|
ICU admission |
33 (13.8%) |
19 (16.8%) |
14 (11.1%) |
0.20 |
Septic shock |
25 (10.5%) |
11 (9.7%) |
14 (11.1%) |
0.73 |
ECMO |
1 (0.4%) |
0 (0.0%) |
1 (0.8%) |
0.34 |
CRRT |
16 (6.7%) |
8 (7.1%) |
8 (6.3%) |
0.82 |
Invasive mechanical
ventilation
|
36 (15.1%)
|
18 (15.9%)
|
18 (14.3%)
|
0.72
|
Corticosteroid therapy |
55 (23.0%) |
30 (26.5%) |
25 (19.8%) |
0.22 |
Outcome |
|
|
|
|
Progress to critical illness |
45 (18.8%) |
24 (21.2%) |
21 (16.7%) |
0.37 |
Day 28 mortality |
33 (13.8%) |
21 (18.6%) |
12 (9.5%) |
0.04 |