5. Conclusion
We described the efficacy of probiotics for the prevention or treatment
of viral-based infectious diseases; more than 20 strains improved the
anti-inflammatory interleukins and anti-body production against viruses.
Moreover, virus titres were lowered after probiotics supplementation
periods. The large number of viral species and their subtypes as well as
the high mutation rate of viruses do not allow scientists to discover
appropriate vaccines and antiviral drugs, so, the administration of
pro/prebiotics - as immune function modulators and antibiotic-related
side effects removers – is recommended. Although further detailed
research is necessary, the authors recommend
researchers/physicians/dietitians to use probiotics as more rational
adjunctive option in COVID-19 pandemic, especially in mechanically
ventilated patients.