Condensed Abstract
A subgroup of patients with frequent (20% <) premature ventricular contractions (PVCs) from the mitral annulus (MA) (MA-PVCs) that significantly caused left ventricular (LV) dilation and deterioration of the clinical status as compared to that in the subgroup with rare (≤ 20%) MA-PVCs. Furthermore, the RFCA of these arrhythmias was associated with a normalization of those abnormalities without any adverse effects. In addition, interestingly, because the MA-PVCs were successfully eliminated by radiofrequency catheter ablation (RFCA) from not only the ventricular side of the MA or coronary sinus but also the left atrial side of the MA, it may be necessary to initially consider a trans-interatrial septal approach to ablate these PVCs.