Figure 6. Canonical pathway analysis of phosphoproteomics in the livers of OSI-906- and linagliptin-treated mice.
A canonical pathway analysis of the hepatic phosphoproteomic data was performed using molecules that were differentially expressed (ANOVAP < 0.05) in comparisons of OSI-906 vs. Vehicle or OSI-906 + Lina vs. OSI-906. The color of the bar indicates the z-score (orange, positive z-score; blue, negative z-score)