Figure 5. Canonical pathway analysis of proteomics in the livers
of OSI-906- and linagliptin-treated mice.
A canonical pathway analysis of the hepatic proteomic data was performed
using molecules that were differentially expressed (ANOVA P< 0.05) in comparisons of OSI-906 vs. Vehicle and OSI-906 +
Lina vs. OSI-906. The color of the bar indicates the z-score (orange,
positive z-score; blue, negative z-score).