Methods
We performed a retrospective cohort study that included all infants with
one or more wheezing episodes who were younger than two years old in
tertiary centers in Rionegro, Colombia, between January 2019 and
December 2019. The municipality of Rionegro had a total population of
101,046 inhabitants, with two tertiary referral hospitals(8). Inclusion
criteria were defined as children younger than two years of age admitted
to the pediatric ward diagnosed with a wheezing episode. Patients
without lower respiratory compromises, with positive bacterial cultures
on admission or a confirmed whooping cough (culture or PCR) were
excluded. The study protocol was approved by the Institutional Review
Board of the University of Antioquia (No 18/2015).