Freedom from atrial tachyarrhythmia
The outcome of AT recurrences was available in all 5 studies [10-12, 14, 15]. Patients who underwent catheter ablation for pulmonary vein isolation had an increased freedom from AT during the 12-24 months follow-up period (pooled HR=0.48, 95% CI: 0.40-0.59, p<0.001, I2=0.0%) compared to AAD therapy (Figure 2). In the subgroup analysis of ablation method, patients in the cryoablation group (pooled HR=0.49, 95%CI: 0.38-0.64, p<0.001, I2=0.0%) (Figure 2A) and radiofrequency ablation group (pooled HR=0.47, 95%CI:0.35-0.64, p<0.001, I2=0.0%) (Figure 2B) both had increased freedom from AT during the 12-24 months follow-up period compared to AAD therapy.