6. Conclusions
In this updated systematic review
and meta-analysis of RCTs, that now includes RCTs that specifically use
cryoballoon ablation only, we found that catheter ablation is more
effective than AADs as an initial therapy for pAF in reducing AT
recurrences over 1-2 years following the treatment initiation. These
results are the same with use of both cryoablation and radiofrequency
ablation approaches. The adverse event rates are low with contemporary
use of AADs and with evolved catheter ablation tools and there were no
differences in any adverse events between the two groups.