Pharmacokinetic calculations
Under fasted and postprandial states, rasagiline PK, measured using the
geometric mean AUC0-t , AUC0-∞ , and
Cmax , were similar between test drug and reference drug
(Table 2 and Table 3). The mean rasagiline plasma concentration-time
profiles stratified by treatment are depicted in Figure 2 and Figure 3.
Median Tmax was similar between the test drug and
reference drug. The detailed pharmacokinetic parameters of the two
rasagiline tablets using single dosing under fasted and postprandial
conditions are presented in Table 2 and Table 3.