Variables Overall DHCA+DR MHCA+ACP p-value
n=210 n=59 n=151
Primary endpoints
Death 14(6.7) 1(1.7) 13(8.6) 0.072
Neurologic events 17(8.1) 1(1.7) 16(10.6) 0.034
Type of NE 0.036
Stroke 14(6.7) 1(1.7) 13(8.6)
Seizures 3(1.4) 0 3(2)
NE symptoms 0.094
Temporary 7(3.3) 0 7(4.5)
Permanent 10(4.8) 1(1.7) 9(6)
NE timing 0.010
Early 16(7.6) 0 16(10.6)
Delayed 1(0.5) 1(1.7) 0
Death and/or PNDs Composite primary endpoints§ 21(10) 35(19.2) 2(3.4) 2(3.4) 19(12.6) 33(21.9) 0.046 0.001
Secondary endpoints
Time to extubation (min) 800(460-1185) 590(360-892) 938(523-1445) <0.001
Tracheostomy 17(8.1) 0(0) 17(11.3) 0.007
ICU LOS 3(2-7) 2(1-3) 4(2-10) <0.001
Other results
Confusion 6(2.9) 0 6(4) 0.121
Bleeding 24h (ml) 590(460-800) 540(442-700) 600(460-835) 0.051
Blood transfusion <0.001
No 71(38.8) 37(62.7) 41(27.2)
Yes 129 (61.2) 22(37.3) 110(72.8)
Blood units 1(0-3) 0(0-1.8) 1.5(0-3) <0.001
Redo bleeding 14(6.7) 3(5.1) 11(7.3) 0.567
Creatinine (peak value, mg/dl) KDIGO score
1.3(1-1.9)
1.1(0.9-1.5)
1.4(1.1-2.1)
<0.001 <0.001
0 129(61.4) 49(83.1) 80(53)
1 35(16.7) 8(13.6) 27(17.9)
2 26(12.4) 2(3.4) 24(15.9)
3 20(9.5) 0(0) 20(13.2)
In-hospital LOS 14(8-24) 11(8-18) 14(8-25) 0.127