Acknowledgements
We thank Professor Stephen Luzio for insulin measurements at the Diabetes Research Unit, Swansea University. We thank Professor Paul B Morgan and members of the Cardiff Complement Biology Group for helpful discussions and reviewing aspects of the work, and Dr Joanna Giles and Dr Rowan Orme for their help with complement assays. We also thank Dr Elizabeth Ellins (Swansea University) and staff at the Clinical Research Facility, University Hospital of Wales for their care of patients and volunteers during the study.