·       Many low-grade tumors can be observed with serial imaging at 3 months

            o   Low to intermediate grade liposarcomas

            o   Low-grade chondrosarcomas

            o   Dermatofibrosarcoma protuberans

            o   Desmoid tumors

 

·       Advanced stage/High grade sarcomas

            o   Consider preoperative chemotherapy and/or radiation therapy

            o   Evaluate closely for immunosuppression risk

·       Osteosarcoma or other sarcomas that are not candidates for preoperative chemotherapy (or for extending active preoperative chemotherapy) should proceed to surgery