Phenotype |
6.7 kb deletion |
6.7 kb deletion |
6.7 kb deletion |
6.7 kb
deletion |
|
rs103294 |
rs103294 |
rs103294 |
rs103294 |
rs103294 |
rs103294 |
|
|
rs410852 |
rs410852 |
rs410852 |
rs410852 |
rs410852 |
rs410852 |
rs410852 |
rs410852 |
|
-/-,-/+ VS +/+ |
-/-,-/+ VS +/+ |
P |
OR(95%CI) |
|
TT,CT VS CC |
TT,CT VS CC |
P |
P |
OR(95%CI) |
OR(95%CI) |
|
|
|
GG,AG VS AA |
GG,AG VS AA |
GG,AG VS AA |
P |
P |
OR(95%CI) |
OR(95%CI) |
dHC (N)
|
450 |
59 |
Ref |
Ref |
|
453 |
56 |
56 |
Ref |
Ref |
Ref |
Ref |
|
|
|
495 |
14 |
14 |
Ref |
Ref |
Ref |
CD (N) |
169 |
16 |
|
|
|
165 |
20 |
20 |
|
|
|
|
|
|
|
176 |
9 |
9 |
|
|
|
Diagnosis age e(yr)
<17
|
13
|
2
|
1.00
|
0.79(0.19-3.87)
|
|
12
|
2
|
2
|
1.00
|
1.00
|
0.74(0.16-3.40)
|
0.74(0.16-3.40)
|
|
|
|
14
|
0
|
0
|
1.00
|
1.00
|
1.03(1.01-1.04)
|
17-40 |
122 |
10 |
|
1.60(0.80-3.22) |
|
113 |
13 |
13 |
0.83 |
0.83 |
1.08(0.57-2.03) |
1.08(0.57-2.03) |
|
|
|
120 |
6 |
6 |
0.38 |
0.38 |
0.57(0.21-1.50) |
>40 |
34 |
4 |
1.00 |
1.11(0.38-3.25) |
|
40 |
5 |
5 |
1.00 |
1.00 |
0.99(0.38-2.61) |
0.99(0.38-2.61) |
|
|
|
42 |
3 |
3 |
0.31 |
0.31 |
0.40(0.11-1.43) |
Site of disease |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
L1 Ileal
L2 Colonic
L3 Ileocolitis
L4 Upper fGI
|
45
51
69
4
|
3
8
5
0
|
0.26
0.66
0.21
1.00
|
1.97(0.59-6.53)
0.84(0.38-1.85)
1.81(0.70-4.67)
1.13(1.10-1.17)
|
|
43
51
67
4
|
5
8
7
0
|
5
8
7
0
|
0.90
0.56
0.69
1.00
|
0.90
0.56
0.69
1.00
|
1.06(0.40-2.80)
0.79(0.36-1.75)
1.18(0.52-2.70)
1.12(1.09-1.16)
|
1.06(0.40-2.80)
0.79(0.36-1.75)
1.18(0.52-2.70)
1.12(1.09-1.16)
|
|
|
|
45
56
71
4
|
3
3
3
0
|
3
3
3
0
|
0.36
0.55
0.80
1.00
|
0.36
0.55
0.80
1.00
|
0.42(0.12-1.53)
0.53(0.15-1.89)
0.67(0.19-2.39)
1.03(1.01-1.04)
|
Disease behavior |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
B1 Non-stricturing/
Non-penetrating
B2 Stricturing
B3 Penetrating
Perianal disease
UC (N)
|
114
33
22
26
175
|
11
4
1
1
18
|
0.37
1.00
0.46
0.34
|
1.36(0.69-2.67)
1.08(0.37-3.16)
2.88(0.38-21.79)
3.41(0.45-25.59)
|
|
113
31
21
25
172
|
12
6
2
2
21
|
12
6
2
2
21
|
0.65
0.49
0.99
0.79
|
0.65
0.49
0.99
0.79
|
1.16(0.60-2.25)
0.64(0.26-1.60)
1.30(0.30-5.68)
1.55(0.36-6.70)
|
1.16(0.60-2.25)
0.64(0.26-1.60)
1.30(0.30-5.68)
1.55(0.36-6.70)
|
|
|
|
122
33
21
26
187
|
3
4
3
1
6
|
3
4
3
1
6
|
1.00
0.03
0.04
0.54
|
1.00
0.03
0.04
0.54
|
1.12(0.33-4.07)
0.23(0.07-0.75)
0.20(0.05-0.74)
0.74(0.09-5.81)
|
Diagnosis age (yr)
<17
17-40
>40
Disease location
E1 Proctitis
E2 Left-sided
E3 Extensive
|
3
96
76
19
70
86
|
0
8
10
4
8
6
|
1.00
0.25
0.99
0.61
0.73
0.15
|
1.13(1.10-1.17)
1.57(0.73-3.40)
1.00(0.49-2.03)
0.62(0.21-1.89)
1.15(0.53-2.50)
1.88(0.79-4.49)
|
|
22
73
77
19
68
85
|
0
10
11
4
10
7
|
0
10
11
4
10
7
|
0.20
0.78
0.68
0.54
0.64
0.33
|
0.20
0.78
0.68
0.54
0.64
0.33
|
1.12 (1.09-1.16)
0.90 (0.44-1.85)
0.87 (0.43-1.73)
0.59 (0.19-1.79)
0.84 (0.41-1.73)
1.50 (0.62-3.41)
|
1.12 (1.09-1.16)
0.90 (0.44-1.85)
0.87 (0.43-1.73)
0.59 (0.19-1.79)
0.84 (0.41-1.73)
1.50 (0.62-3.41)
|
|
|
|
2
101
84
22
76
89
|
0
2
4
1
2
3
|
0
2
4
1
2
3
|
1.00
0.90
0.57
0.49
1.00
1.00
|
1.00
0.90
0.57
0.49
1.00
1.00
|
1.03 (1.01-1.04)
1.43 (0.32-6.38)
0.59 (0.19-1.85)
0.62 (0.08-4.95)
1.08 (0.24-4.82)
0.84 (0.24-2.98)
|