Discussion
The major findings of this study
are as follows. The incidence of SCEs remains at 23.1% in patients on
uninterrupted OAC for AF ablation. In multivariate analysis, LAD,
baseline ACT before UFH injection, and time to reach optimal ACT were
significant risk factors for SCEs. Finally, the average values of the
baseline ACT and the time to reach the optimal ACT were significantly
different between patients with different oral anticoagulants.
Intra-procedural ACT kinetics affect the incidence of SCEs and vary
among anticoagulants in patients on uninterrupted OAC, which should be
considered when estimating the risk of SCEs.