Risk Factors for SCEs
Significant univariate factors were age, persistent AF,
CHADS2/CH2ADS2-VASc
score, serum NT-ProBNP levels, LAD, spontaneous echo contrast, baseline
ACT before first UFH injection, and time to reach the optimal ACT
(> 300 sec), all of which were directed to multivariate
analysis. CHADS2 score (> 2 points or
<2 points) and CH2ADS2-VASc
score (> 3 points or <3 points) were
considered as categorical data based on the clinical risk stratification
of thromboembolism. LAD was also considered as categorical data with a
clinical cut-off value of 40 mm. After adjusting for age and gender,
multivariate logistic analysis demonstrated that LAD, and the baseline
ACT, and the time to reach the optimal ACT were significant risk factors
for SCEs (Table 2).