Discussion
The major findings of this study are as follows. The incidence of SCEs remains at 23.1% in patients on uninterrupted OAC for AF ablation. In multivariate analysis, LAD, baseline ACT before UFH injection, and time to reach optimal ACT were significant risk factors for SCEs. Finally, the average values of the baseline ACT and the time to reach the optimal ACT were significantly different between patients with different oral anticoagulants. Intra-procedural ACT kinetics affect the incidence of SCEs and vary among anticoagulants in patients on uninterrupted OAC, which should be considered when estimating the risk of SCEs.